| Moero 6!! Shin Moero!! Pro Yakyuu | Nintendo Entertainment System | 1989 | Jaleco |
| Moero 7!! Juudou Warriors | Nintendo Entertainment System | 1990 | Jaleco |
| Mohawk & Headphone Jack | Super Nintendo Entertainment System | 1996 | — |
| Mole Mania | Game Boy | 1996 | Nintendo Entertainment Analysis & Development |
| Mom-chan Diet Wii Figureobics by Jung Da-Yeon | Wii | 2010 | Mechanic Arms |
| Momoko 120% | Nintendo Entertainment System | 1986 | Jaleco |
| Momotaro Dentetsu | Nintendo Entertainment System | 1988 | Hudson Soft |
| Momotaro Dentetsu 11: Black Bombee Arrives | Nintendo GameCube | 2002 | Hudson Soft |
| Momotaro Dentetsu 12: All Aboard for Western Japan! | Nintendo GameCube | 2003 | Hudson Soft |
| Momotaro Dentetsu 16: Moving in Hokkaido! | Wii | 2007 | Hudson Soft |
| Momotaro Dentetsu 2017: Tachiagare Nippon!! | Nintendo 3DS | 2016 | — |
| Momotaro Dentetsu HAPPY | Super Nintendo Entertainment System | 1996 | — |
| Monkey Mischief: Party Time | Wii | 2008 | Nordcurrent |
| Monochrome Racing | PlayStation Vita, Wii | 2011 | Nordcurrent |
| Monopoly | Super Nintendo Entertainment System | 1992 | — |
| Monopoly | Wii | 2008 | Electronic Arts |
| Monopoly | Nintendo Entertainment System | 1991 | Sculptured Software |
| Monopoly Party! | Nintendo GameCube | 2002 | Runecraft |
| Monopoly Streets | Wii | 2010 | EA Salt Lake |
| Monsteca Corral | Wii | 2010 | Onteca (United Kingdom) |
| Monster 4x4 3D | Nintendo 3DS | 2012 | — |
| Monster 4x4: Masters of Metal | Nintendo GameCube | 2003 | Ubisoft Barcelona |
| Monster 4x4: Stunt Racer | Wii | 2009 | Ubisoft |
| Monster 4x4: World Circuit | Wii | 2006 | Ubisoft Barcelona |
| Monster High: 13 Wishes | Wii | 2013 | Game Machine Studios |
| Monster High: Ghoul Spirit | Wii | 2011 | ImaginEngine |
| Monster House | Nintendo GameCube | 2006 | Behaviour Interactive |
| Monster Hunter 3 | Wii | 2009 | Capcom |
| Monster Hunter 4 | Nintendo 3DS | 2013 | Capcom |
| Monster Hunter 4 Ultimate | Nintendo 3DS | 2014 | — |
| Monster Hunter G | Wii | 2005 | Capcom |
| Monster Hunter Generations | Nintendo 3DS | 2015 | Capcom |
| Monster Hunter Generations Ultimate | Nintendo 3DS | 2017 | — |
| Monster Hunter Stories | Nintendo 3DS | 2016 | Capcom, Marvelous |
| Monster Hunter XX | Nintendo 3DS | 2017 | Capcom |
| Monster in My Pocket | Nintendo Entertainment System | 1992 | Konami |
| Monster Jam | Wii | 2007 | Torus Games |
| Monster Jam: Maximum Destruction | Nintendo GameCube | 2002 | Inland Productions |
| Monster Jam: Path of Destruction | Wii | 2010 | Virtuos |
| Monster Jam: Urban Assault | Wii | 2008 | Torus Games |
| Monster Lab | Wii | 2008 | Backbone Entertainment |
| Monster Max | Game Boy | 1994 | Rare Ltd. |
| Monster Mayhem: Build and Battle | Wii | 2009 | Brain Toys |
| Monster Party | Nintendo Entertainment System | 1989 | Human Entertainment |
| Monster Shooter | Nintendo 3DS | 2012 | — |
| Monster Truck | Game Boy | 1990 | — |
| Monster Truck Rally | Nintendo Entertainment System | 1991 | Realtime Associates |
| Monster Truck Wars | Game Boy | 1994 | — |
| Monster Trucks Mayhem | Wii | 2009 | Zoo Corporation |
| Monster Trux Extreme: Offroad Edition | Wii | 2005 | Data Design Interactive |
| Monster Trux: Arenas | Wii | 2007 | Data Design Interactive |
| Monster Trux: Offroad | Wii | 2007 | Data Design Interactive |
| Monsters vs. Aliens | Wii | 2009 | Beenox |
| Monsters, Inc. Scream Arena | Nintendo GameCube | 2002 | Radical Entertainment |
| Moon Cresta | Super Nintendo Entertainment System | 1980 | Nichibutsu |
| Moon Crystal | Nintendo Entertainment System | 1992 | Hect |
| Moon Ranger | Nintendo Entertainment System | 1990 | Odyssey Software |
| Moonbound | Nintendo 3DS | 2021 | — |
| Mortal Kombat | Super Nintendo Entertainment System, Game Boy | 1992 | Midway Games |
| Mortal Kombat 3 | Super Nintendo Entertainment System, Game Boy | 1995 | Midway Games |