| My Word Coach | Wii | 2007 | Ubisoft Montreal |
| MySims | Wii | 2007 | Visceral Games, Tose Co., Babaroga |
| MySims Agents | Wii | 2009 | Visceral Games, Tose Co. |
| MySims Kingdom | Wii | 2008 | Visceral Games, Tose Co. |
| MySims Party | Wii | 2009 | Hudson Soft, Visceral Games |
| MySims Racing | Wii | 2009 | Behaviour Interactive |
| MySims SkyHeroes | Wii | 2010 | Behaviour Interactive |
| Myst | Nintendo 3DS | 1993 | Cyan Worlds |
| Mysterium | Game Boy | — | Maxis |
| Mystery Case Files: Dire Grove | Nintendo 3DS | 2009 | Big Fish Games |
| Mystery Case Files: Return to Ravenhearst | Nintendo 3DS | 2008 | Big Fish Games |
| Mystery Case Files: The Malgrave Incident | Wii | 2011 | Big Fish Games |
| Mystery Circle | Super Nintendo Entertainment System | 1992 | — |
| Mystery Dungeon: Shiren the Wanderer | Super Nintendo Entertainment System, Game Boy | 1995 | Chunsoft |
| Mystery Quest | Nintendo Entertainment System | 1987 | Carry Lab |
| Mystery Tower | Nintendo Entertainment System | 1986 | Namco |
| Mystic Ark | Super Nintendo Entertainment System | 1995 | Produce! |
| Mystic Heroes | Nintendo GameCube | 2002 | Koei |
| Mystical Ninja Starring Goemon | Game Boy | 1997 | Konami |
| Myth Makers: Orbs of Doom | Wii | 2007 | Data Design Interactive |
| Myth Makers: Super Kart GP | Wii | 2006 | Data Design Interactive |
| Myth Makers: Trixie in Toyland | Wii | 2005 | Data Design Interactive |
| Märchen Adventure Cotton 100% | Super Nintendo Entertainment System | 1994 | Success |
| Mōko Densetsu 95: Hanshin Tigers | Super Nintendo Entertainment System | 1995 | — |
| Mōryō Senki Madara 2 | Super Nintendo Entertainment System | 1993 | Konami |
| Nadia: The Secret of Blue Water | Nintendo Entertainment System | 1991 | Advance Communication |
| Nagagutsu o Haita Neko: Sekai Isshū 80 Nichi Dai Bōken | Nintendo Entertainment System | 1986 | Shōei |
| Nage Libre: Seijaku no Suishin | Super Nintendo Entertainment System | 1995 | — |
| Nail 'n' Scale | Game Boy | 1990 | Data East |
| Nakajima Satoru F-1 Hero '94 | Super Nintendo Entertainment System | 1994 | — |
| Nakano Kōichi Kanshū: Keirin Ō | Super Nintendo Entertainment System | 1994 | — |
| Nakayoshi to Issho | Nintendo Entertainment System | 1993 | Yutaka |
| Namco Museum | Nintendo GameCube | 2002 | — |
| Namco Museum Megamix | Wii | 2010 | — |
| Namco Museum Remix | Wii | 2007 | Bandai Namco Entertainment |
| Namco Museum: 50th Anniversary | Nintendo GameCube | 1955 | — |
| Namco Open | Super Nintendo Entertainment System | 1993 | Tose Co. |
| Nancy Drew: The White Wolf of Icicle Creek | Wii | 2007 | Her Interactive |
| Nano Assault | Nintendo 3DS | 2011 | — |
| Nantettatte!! Baseball | Nintendo Entertainment System | 1990 | Sunsoft |
| Napoleon Senki | Nintendo Entertainment System | 1988 | Lenar |
| Narc | Nintendo Entertainment System | 1988 | WMS Industries |
| Naruhodo! The World | Super Nintendo Entertainment System | 1994 | Tomy |
| Naruto Powerful Shippūden | Nintendo 3DS | 2012 | — |
| Naruto Shippūden 3D: The New Era | Nintendo 3DS | 2011 | Tomy |
| Naruto Shippūden: Clash of Ninja Revolution 3 | Wii | 2009 | Eighting |
| Naruto Shippūden: Dragon Blade Chronicles | Wii | 2009 | Tomy |
| Naruto Shippūden: Gekitō Ninja Taisen! EX | Wii | 2007 | Eighting |
| Naruto Shippūden: Gekitō Ninja Taisen! EX 2 | Wii | 2007 | Eighting |
| Naruto Shippūden: Gekitō Ninja Taisen! EX 3 | Wii | 2008 | Eighting |
| Naruto Shippūden: Gekitō Ninja Taisen! Special | Wii | 2010 | Eighting |
| Naruto: Clash of Ninja | Nintendo GameCube | 2003 | Eighting |
| Naruto: Clash of Ninja 2 | Nintendo GameCube | 2003 | — |
| Naruto: Clash of Ninja Revolution | Wii | 2007 | Eighting |
| Naruto: Clash of Ninja Revolution 2 | Wii | 2008 | Eighting |
| Naruto: Gekitō Ninja Taisen! 3 | Nintendo GameCube | 2004 | — |
| Naruto: Gekitō Ninja Taisen! 4 | Nintendo GameCube | 2005 | — |
| NASCAR 2005: Chase for the Cup | Nintendo GameCube | 2004 | Electronic Arts |
| NASCAR Kart Racing | Wii | 2009 | Electronic Arts |
| NASCAR The Game: 2011 | Wii | 2011 | Eutechnyx |