| M&M's Adventure | Wii | 2008 | Nikitova Games |
| M&M's Beach Party | Wii | 2009 | Digital Embryo |
| M&M's Kart Racing | Wii | 2007 | FrontLine Studios |
| M.C. Kids | Nintendo Entertainment System, Game Boy | 1992 | Visual Concepts, Virgin Interactive, Arc Developments |
| M.U.L.E. | Nintendo Entertainment System | 1983 | Ozark Softscape |
| MaBoShi: The Three Shape Arcade | Wii | 2008 | Mindware Corp. |
| Mach Rider | Nintendo Entertainment System | 1985 | Nintendo Research & Development 2 |
| Machine Knight | Nintendo 3DS | 2012 | — |
| Mad Dog II: The Lost Gold | Wii | 1992 | American Laser Games |
| Mad Dog McCree | Wii | 1993 | American Laser Games |
| Mad Max | Nintendo Entertainment System | 1990 | Mindscape |
| Mad Tracks | Wii | 2007 | Load Inc. |
| Madagascar | Nintendo GameCube | 2005 | Toys for Bob |
| Madagascar 3: The Video Game | Nintendo 3DS, Wii | 2012 | Monkey Bar Games |
| Madagascar Kartz | Wii | 2009 | Sidhe |
| Madagascar: Escape 2 Africa | Wii | 2008 | Toys for Bob |
| Madden NFL '94 | Super Nintendo Entertainment System | 1993 | EA Orlando |
| Madden NFL '95 | Super Nintendo Entertainment System, Game Boy | 1994 | Electronic Arts |
| Madden NFL '96 | Super Nintendo Entertainment System | 1995 | EA Orlando |
| Madden NFL 06 | Nintendo GameCube | 2005 | EA Orlando |
| Madden NFL 07 | Nintendo GameCube, Wii | 2006 | EA Orlando |
| Madden NFL 08 | Nintendo GameCube, Wii | 2007 | EA Orlando |
| Madden NFL 09 | Wii | 2008 | EA Orlando |
| Madden NFL 10 | Wii | 2009 | EA Orlando |
| Madden NFL 11 | Wii | 2010 | EA Orlando |
| Madden NFL 12 | Wii | 2011 | EA Orlando |
| Madden NFL 13 | PlayStation Vita, Wii | 2012 | EA Orlando |
| Madden NFL 2002 | Nintendo GameCube | 2001 | EA Orlando |
| Madden NFL 2003 | Nintendo GameCube | 2002 | EA Orlando |
| Madden NFL 2004 | Nintendo GameCube | 2003 | EA Orlando |
| Madden NFL 2005 | Nintendo GameCube | 2004 | EA Orlando |
| Madden NFL 97 | Super Nintendo Entertainment System, Game Boy | 1996 | EA Orlando |
| Madden NFL 98 | Super Nintendo Entertainment System | 1997 | EA Orlando |
| Madden NFL Football | Nintendo 3DS | 2011 | EA Sports |
| MadStone | Wii | 2008 | RiverMan Media |
| MadWorld | Wii | 2009 | PlatinumGames |
| Madō Monogatari: Hanamaru Daiyōchienji | Super Nintendo Entertainment System | 1996 | Compile |
| Magic Boy | Super Nintendo Entertainment System | 1993 | Empire Interactive |
| Magic Darts | Nintendo Entertainment System | 1991 | Romstar |
| Magic Jewelry | Nintendo Entertainment System | 1990 | Hwang Shinwei |
| Magic Johnson's Fast Break | Nintendo Entertainment System | 1988 | Arcadia Systems |
| Magic Knight Rayearth | Super Nintendo Entertainment System | 1995 | — |
| Magic Sword: Heroic Fantasy | Super Nintendo Entertainment System | 1990 | Capcom |
| Magical Drop | Super Nintendo Entertainment System | 1995 | Data East |
| Magical Drop II | Super Nintendo Entertainment System | 1996 | — |
| Magical Pop'n | Super Nintendo Entertainment System | 1995 | — |
| Magical Tarurūto-kun: Magic Adventure | Super Nintendo Entertainment System | 1992 | Game Freak |
| Magician | Nintendo Entertainment System | 1991 | Eurocom |
| MagMax | Nintendo Entertainment System | 1986 | Nichibutsu |
| Magna Braban: Henreki no Yusha | Super Nintendo Entertainment System | 1994 | — |
| Magnetic Soccer | Game Boy | 1992 | — |
| Mahjong 3D Essentials | Nintendo 3DS | 2013 | YipYip |
| Mahjong 3D Warriors of the Emperor | Nintendo 3DS | 2012 | YipYip |
| Mahjong Cub3d | Nintendo 3DS | 2011 | Sunsoft |
| Mahjong Taikai Wii | Wii | 2007 | Koei |
| Mahjong Wii | Wii | 2007 | Koei |
| Mahōjin Guru Guru | Super Nintendo Entertainment System | 1995 | — |
| Mahōjin Guru Guru 2 | Super Nintendo Entertainment System | 1996 | — |
| Majin Bone: Jikan to Kūkan no Majin | Nintendo 3DS | 2014 | — |
| Majin Tensei | Super Nintendo Entertainment System | 1994 | Atlus |
| Majin Tensei II: Spiral Nemesis | Super Nintendo Entertainment System, Wii | 1995 | Atlus |
| Majo-tachi no Nemuri | Super Nintendo Entertainment System | 1995 | — |
| Major Dream: Major Wii Nagero! Gyroball!! | Wii | 2008 | DreamFactory |
| Major League Baseball | Nintendo Entertainment System | 1988 | Atlus |
| Major League Baseball 2K10 | Wii | 2010 | Visual Concepts |
| Major League Baseball 2K11 | Wii | 2011 | Visual Concepts |
| Major League Baseball 2K12 | Wii | 2012 | Visual Concepts |
| Major League Baseball 2K6 | Nintendo GameCube | 2006 | Visual Concepts |
| Major League Baseball 2K8 | Wii | 2008 | 2K Los Angeles |
| Major League Baseball 2K9 | Wii | 2009 | Visual Concepts |
| Major Minor's Majestic March | Wii | 2009 | NanaOn-Sha |
| Major Title | Super Nintendo Entertainment System | 1992 | Irem |
| Major Wii: Perfect Closer | Wii | 2008 | DreamFactory |
| Majyūō | Super Nintendo Entertainment System | 1995 | KSS |
| Majō Densetsu II: Daimashikyō Galious | Nintendo Entertainment System | 1987 | Konami |
| Maka Maka | Super Nintendo Entertainment System | 1992 | Shōei System, Office Koukan |
| Makeruna! Makendō 2: Kimero Youkai Souri | Super Nintendo Entertainment System | 1995 | Success |
| Man vs. Wild | Wii | 2011 | Scientifically Proven |
| Manchester United Championship Soccer | Super Nintendo Entertainment System | — | Krisalis Software |
| Manhunt 2 | Wii | 2007 | Rockstar London |
| Maniac Mansion | Nintendo Entertainment System, Apple II series | 1987 | Lucasfilm Games |
| Mappy | Nintendo Entertainment System | 1984 | Namco |
| Mappy Kids | Nintendo Entertainment System | 1989 | Namco |
| Mappy-Land | Nintendo Entertainment System | 1986 | Tose Co. |
| Marble Madness | Nintendo Entertainment System, Game Boy | 1984 | Atari Games |
| Marble Saga: Kororinpa | Wii | 2009 | Hudson Soft |
| Margot's Word Brain | Wii | 2008 | Slam Games |
| Marines: Modern Urban Combat | Wii | 2009 | Destineer |
| Mario & Luigi: Bowser's Inside Story + Bowser Jr.'s Journey | Nintendo 3DS | 2018 | — |
| Mario & Luigi: Dream Team | Nintendo 3DS | 2013 | AlphaDream |
| Mario & Luigi: Paper Jam | Nintendo 3DS | 2015 | AlphaDream |
| Mario & Luigi: Superstar Saga + Bowser's Minions | Nintendo 3DS | 2017 | — |
| Mario & Sonic at the London 2012 Olympic Games | Nintendo 3DS, Wii | 2011 | Sega Sports R&D |
| Mario & Sonic at the Olympic Games | Wii | 2007 | Sega Sports R&D |
| Mario & Sonic at the Olympic Winter Games | Wii | 2009 | Sonic Team, Racjin |
| Mario & Sonic at the Rio 2016 Olympic Games | Nintendo 3DS | 2016 | Sega Sports R&D |
| Mario & Wario | Super Nintendo Entertainment System | 1993 | Game Freak |
| Mario and Donkey Kong: Minis on the Move | Nintendo 3DS | 2013 | Nintendo Software Technology |
| Mario Bros. | Nintendo Entertainment System | 1984 | Nintendo |
| Mario Golf: Toadstool Tour | Nintendo GameCube | 2003 | Camelot Software Planning |
| Mario Golf: World Tour | Nintendo 3DS | 2014 | Camelot Software Planning |
| Mario Is Missing! | Nintendo Entertainment System, Super Nintendo Entertainment System | 1993 | The Software Toolworks |
| Mario Kart 7 | Nintendo 3DS | 2011 | Nintendo Entertainment Analysis & Development, Retro Studios |
| Mario Kart Wii | Wii | 2008 | Nintendo Entertainment Analysis & Development |
| Mario Kart: Double Dash | Nintendo GameCube | 2003 | Nintendo Entertainment Analysis & Development |
| Mario Paint | Super Nintendo Entertainment System | 1992 | Nintendo Research & Development 1 |
| Mario Party 4 | Nintendo GameCube | 2002 | Hudson Soft |
| Mario Party 5 | Nintendo GameCube | 2003 | Hudson Soft |
| Mario Party 6 | Nintendo GameCube | 2004 | Hudson Soft |
| Mario Party 7 | Nintendo GameCube | 2005 | Hudson Soft |
| Mario Party 8 | Wii | 2007 | Hudson Soft |
| Mario Party 9 | Wii | 2012 | Nintendo Cube |
| Mario Party: Island Tour | Nintendo 3DS | 2013 | Nintendo Cube |
| Mario Party: Star Rush | Nintendo 3DS | 2016 | Nintendo Cube |
| Mario Party: The Top 100 | Nintendo 3DS | 2017 | Nintendo Cube |
| Mario Power Tennis | Nintendo GameCube, Wii | 2004 | Camelot Software Planning |
| Mario Sports Mix | Wii | 2010 | Square Enix |
| Mario Sports Superstars | Nintendo 3DS | 2017 | Bandai Namco Entertainment |
| Mario Strikers Charged | Wii | 2007 | Next Level Games |
| Mario Super Sluggers | Wii | 2008 | Bandai Namco Entertainment |
| Mario Superstar Baseball | Nintendo GameCube | 2005 | Namco |
| Mario Tennis Open | Nintendo 3DS | 2012 | Camelot Software Planning |
| Mario vs. Donkey Kong: Tipping Stars | Nintendo 3DS | 2015 | Nintendo Software Technology |
| Mario's Early Years! Fun with Letters | Super Nintendo Entertainment System | 1993 | — |
| Mario's Early Years! Fun with Numbers | Super Nintendo Entertainment System | 1994 | — |
| Mario's Early Years! Preschool Fun | Super Nintendo Entertainment System | 1994 | — |
| Mario's Picross | Super Nintendo Entertainment System, Game Boy | 1995 | Ape, Inc., Jupiter |
| Mario's Super Picross | Super Nintendo Entertainment System | 1995 | Creatures |
| Mario's Time Machine | Nintendo Entertainment System, Super Nintendo Entertainment System | 1993 | Mindscape |
| Mark Davis Pro Bass Challenge | Nintendo GameCube | 2003 | SIMS Co., Ltd. |
| Mark Davis' The Fishing Master | Super Nintendo Entertainment System | 1995 | Winning Entertainment Group |
| Mart Racer | Wii | 2009 | Joju Games |
| Martian Panic | Wii | 2010 | N-Fusion Interactive |
| Maru's Mission | Game Boy | 1990 | Tose Co. |
| Marvel Land | Wii | 1990 | Namco |
| Marvel Nemesis: Rise of the Imperfects | Nintendo GameCube | 2005 | nStigate Games |
| Marvel Super Hero Squad | Wii | 2009 | Blue Tongue Entertainment |
| Marvel Super Hero Squad: Comic Combat | Wii | 2011 | Griptonite Games |
| Marvel Super Hero Squad: The Infinity Gauntlet | Wii | 2010 | Griptonite Games |
| Marvel Super Heroes 3D: Grandmaster's Challenge | Wii | 2010 | Neko Entertainment |
| Marvel Super Heroes in War of the Gems | Super Nintendo Entertainment System | 1996 | Capcom |
| Marvel: Ultimate Alliance | Wii | 2006 | Raven Software |
| Marvel: Ultimate Alliance 2 | Wii | 2009 | Blizzard Albany |
| Marvelous: Mōhitotsu no Takarajima | Super Nintendo Entertainment System | 1996 | Nintendo Research & Development 2 |
| Mary Shelley's Frankenstein | Super Nintendo Entertainment System | 1994 | Bits Studios |
| Mary-Kate and Ashley: Sweet 16 Licensed to Drive | Nintendo GameCube | 2003 | — |
| Master Chu and the Drunkard Hu | Nintendo Entertainment System | 1989 | Thin Chen Enterprise |
| Master Takahashi's Adventure Island IV | Nintendo Entertainment System | 1994 | Hudson Soft |
| Masuzoe Youichi: Asa Made Famicom | Nintendo Entertainment System | 1992 | Coconuts Japan |
| Mat Hoffman's Pro BMX 2 | Nintendo GameCube | 2002 | THQ |
| Matchman | Wii | 2008 | — |
| Math Blaster Episode I: In Search of Spot | Super Nintendo Entertainment System | 1994 | Davidson & Associates |
| Mathews Bowhunting | Wii | 2010 | Zoo Corporation |
| Matsukata Hiroki no Super Trawling | Super Nintendo Entertainment System | 1995 | — |
| Matsumura Kunihiro Den: Saikyō no Rekishi o Nurikaero! | Super Nintendo Entertainment System | 1994 | — |
| Maui Mallard in Cold Shadow | Super Nintendo Entertainment System, Game Boy | 1995 | Disney Interactive Studios |
| Max & the Magic Marker | Wii | 2010 | Press Play |
| Maximum Racing: Drag & Stock Racer | Wii | 2010 | Brain in a Jar |
| Maximum Racing: GP Classic Racing | Wii | 2010 | Brain in a Jar |
| MaxPlay Classic Games Volume 1 | Nintendo GameCube | 2004 | Action Replay |
| Mazinger Z | Super Nintendo Entertainment System | 1993 | Winkysoft |
| MC Groovz Dance Craze | Nintendo GameCube | 2004 | Mad Catz |
| Mecarobot Golf | Super Nintendo Entertainment System | 1992 | — |
| Mechanized Attack | Nintendo Entertainment System | 1989 | SNK |
| MechWarrior | Super Nintendo Entertainment System | 1993 | Krome Studios Melbourne |
| MechWarrior 3050 | Super Nintendo Entertainment System | 1994 | EA Orlando |
| Medabots Infinity | Nintendo GameCube | 2003 | Victor Interactive Software |
| Medal of Honor: European Assault | Nintendo GameCube | 2005 | Danger Close Games |
| Medal of Honor: Frontline | Nintendo GameCube | 2002 | Danger Close Games |
| Medal of Honor: Heroes 2 | Wii | 2007 | Danger Close Games |
| Medal of Honor: Rising Sun | Nintendo GameCube | 2003 | Danger Close Games |
| Medal of Honor: Vanguard | Wii | 2007 | Budcat Creations |
| Medieval games | Wii | 2009 | N-Fusion Interactive |
| Meet the Robinsons | Nintendo GameCube, Wii | 2007 | Climax Studios |
| Mega Lo Mania | Super Nintendo Entertainment System | 1991 | Sensible Software |
| Mega Man | Nintendo Entertainment System, Nintendo 3DS, Wii | 1987 | Capcom |
| Mega Man & Bass | Super Nintendo Entertainment System | 1998 | Capcom |
| Mega Man 10 | Wii | 2010 | Inti Creates |
| Mega Man 2 | Nintendo Entertainment System | 1988 | Capcom |
| Mega Man 3 | Nintendo Entertainment System | 1990 | Capcom |
| Mega Man 4 | Nintendo Entertainment System | 1991 | Capcom |
| Mega Man 5 | Nintendo Entertainment System | 1992 | Capcom |
| Mega Man 6 | Nintendo Entertainment System | 1993 | Capcom |
| Mega Man 7 | Super Nintendo Entertainment System | 1995 | Capcom |
| Mega Man 9 | Wii | 2008 | Inti Creates |
| Mega Man Anniversary Collection | Nintendo GameCube | 2004 | Atomic Planet Entertainment |
| Mega Man II | Game Boy | 1991 | — |
| Mega Man III | Game Boy | 1992 | Capcom |
| Mega Man IV | Game Boy | 1993 | Capcom |
| Mega Man Legacy Collection | Nintendo 3DS | 2015 | Capcom |
| Mega Man Legends 3 | Nintendo 3DS | — | Capcom |
| Mega Man Network Transmission | Nintendo GameCube | 2010 | Arika |
| Mega Man Soccer | Super Nintendo Entertainment System | 1994 | Capcom |
| Mega Man V | Game Boy | 1994 | Capcom |
| Mega Man X | Super Nintendo Entertainment System, Wii | 1993 | Capcom |
| Mega Man X Collection | Nintendo GameCube | 2006 | Capcom |
| Mega Man X2 | Super Nintendo Entertainment System | 1994 | Capcom |
| Mega Man X3 | Super Nintendo Entertainment System | 1995 | Capcom |
| Mega Man X: Command Mission | Nintendo GameCube | 2004 | Capcom |
| Mega Man Xtreme | Nintendo 3DS | 2000 | Capcom |
| Mega Man: Dr. Wily's Revenge | Game Boy | 1991 | Capcom |
| Megalit | Game Boy | 1991 | ASCII Corporation |
| Megami Meguri | Nintendo 3DS | 2016 | Capcom |
| Megami Tensei Gaiden: Last Bible II | Game Boy, Nintendo 3DS | 1993 | — |
| Megamind: Mega Team Unite | Wii | 2010 | THQ Studio Australia |
| Megamind: Ultimate Showdown | Wii | 2010 | THQ |
| Meitantei Conan - Chika yūenchi satsujin jiken | Game Boy | 1996 | — |
| Meitantei Holmes: M-Kara no Chousenjou | Nintendo Entertainment System | 1989 | Another |
| Melfand Stories | Super Nintendo Entertainment System | 1994 | — |
| Men in Black II: Alien Escape | Nintendo GameCube | 2002 | Krome Studios Melbourne |
| Menace Beach | Nintendo Entertainment System | 1990 | Color Dreams |
| Mendel Palace | Nintendo Entertainment System | 1989 | Game Freak |
| Mercedes-Benz World Racing | Nintendo GameCube | 2003 | Synetic GmbH |
| Mercenary Force | Game Boy | 1990 | — |
| Mercury Meltdown Revolution | Wii | 2007 | UTV Ignition Games |
| Merv Griffin's Crosswords | Wii | 2008 | Pipeworks Software |
| Metal Arms: Glitch in the System | Nintendo GameCube | 2003 | Swingin' Ape Studios |
| Metal Combat: Falcon's Revenge | Super Nintendo Entertainment System | 1993 | Intelligent Systems |
| Metal Fighter | Nintendo Entertainment System | 1989 | Thin Chen Enterprise |
| Metal Gear | Nintendo Entertainment System, Nintendo GameCube, PlayStation Vita | 1987 | Konami |
| Metal Gear Solid: Snake Eater 3D | Nintendo 3DS | 2012 | Kojima Productions |
| Metal Gear Solid: The Twin Snakes | Nintendo GameCube | 2004 | Silicon Knights |
| Metal Marines | Super Nintendo Entertainment System | 1993 | Namco |
| Metal Masters | Game Boy | 1993 | Bit Managers |
| Metal Max | Nintendo Entertainment System, Super Nintendo Entertainment System | 1991 | Crea-Tech |
| Metal Max 2 | Super Nintendo Entertainment System | 1993 | Crea-Tech |
| Metal Max 4: Gekkō no Diva | Nintendo 3DS | 2013 | — |
| Metal Mech | Nintendo Entertainment System | 1990 | Sculptured Software |
| Metal Morph | Super Nintendo Entertainment System | 1994 | Origin Systems |
| Metal Slader Glory | Nintendo Entertainment System, Super Nintendo Entertainment System | 1991 | HAL Laboratory |
| Metal Slug Anthology | Wii | 2006 | Terminal Reality |
| Metal Storm | Nintendo Entertainment System | 1991 | GameFAQs |
| Metal Warriors | Super Nintendo Entertainment System | 1995 | Lucasfilm Games |
| Metro-Cross | Nintendo Entertainment System | 1985 | Namco |
| Metroid | Nintendo Entertainment System | 1986 | Nintendo Research & Development 1 |
| Metroid II: Return of Samus | Game Boy, Nintendo 3DS | 1991 | Nintendo Research & Development 1 |
| Metroid Prime | Nintendo GameCube, Wii | 2002 | Retro Studios |
| Metroid Prime 2: Echoes | Nintendo GameCube, Wii | 2004 | Retro Studios |
| Metroid Prime 3: Corruption | Wii | 2007 | Retro Studios |
| Metroid Prime: Federation Force | Nintendo 3DS | 2016 | Next Level Games |
| Metroid Prime: Trilogy | Wii | 2009 | Retro Studios |
| Metroid: Other M | Wii | 2010 | D-Rockets, Nintendo Software Planning & Development, Team Ninja |
| Metroid: Samus Returns | Nintendo 3DS | 2017 | Nintendo Entertainment Planning & Development, MercurySteam |
| Mezase! Top Pro: Green ni Kakeru Yume | Nintendo Entertainment System | 1993 | Tose Co. |
| MIB: Alien Crisis | Wii | 2012 | Modus Studios Bucharest |
| Miburi & Teburi | Wii | 2008 | Climax Entertainment |
| Michael Andretti's Indy Car Challenge | Super Nintendo Entertainment System | 1994 | Genki |
| Michael Andretti's World GP | Nintendo Entertainment System | 1988 | Human Entertainment |
| Michael Jackson: The Experience | PlayStation Vita, Nintendo 3DS, Wii | 2010 | Ubisoft Montpellier |
| Michael Jordan: Chaos in the Windy City | Super Nintendo Entertainment System | 1994 | Electronic Arts |
| Mickey Mania | Super Nintendo Entertainment System | 1994 | Traveller's Tales |
| Mickey Mouse: Magic Wands! | Game Boy | 1993 | Kemco |
| Mickey Mousecapade | Nintendo Entertainment System | 1987 | Hudson Soft |
| Mickey no Tokyo Disneyland Daibōken | Super Nintendo Entertainment System | 1994 | — |
| Mickey's Adventures in Numberland | Nintendo Entertainment System | 1994 | Krome Studios Melbourne |
| Mickey's Dangerous Chase | Game Boy | 1991 | Now Production |
| Mickey's Safari in Letterland | Nintendo Entertainment System | 1993 | Krome Studios Melbourne |
| Mickey's Ultimate Challenge | Super Nintendo Entertainment System | 1994 | Disney Interactive Studios |
| Micro Machines | Nintendo Entertainment System, Super Nintendo Entertainment System, Game Boy | 1991 | Codemasters |
| Micro Machines | Nintendo GameCube | 2002 | Gremlin Interactive |
| Micro Machines 2: Turbo Tournament | Super Nintendo Entertainment System, Game Boy | 1994 | Codemasters |
| Micro Mages | Nintendo Entertainment System | 2019 | Morphcat Games |
| MIDI Maze | Super Nintendo Entertainment System, Game Boy | 1987 | — |
| Midnight Bowling | Wii | 2008 | Gameloft |
| Midway Arcade Treasures | Nintendo GameCube | 2003 | Backbone Entertainment |
| Midway Arcade Treasures 2 | Nintendo GameCube | 2004 | Backbone Entertainment |
| Midway Arcade Treasures 3 | Nintendo GameCube | 2005 | Midway Games |
| MiG-29: Soviet Fighter | Nintendo Entertainment System | 1989 | Codemasters |
| Might and Magic Book One: The Secret of the Inner Sanctum | Nintendo Entertainment System | 1990 | New World Computing |
| Might and Magic II: Gates to Another World | Super Nintendo Entertainment System | 1988 | New World Computing |
| Might and Magic III: Isles of Terra | Super Nintendo Entertainment System | 1991 | New World Computing |
| Mighty Bomb Jack | Nintendo Entertainment System | 1986 | Tecmo |
| Mighty Final Fight | Nintendo Entertainment System | 1993 | Capcom |
| Mighty Gunvolt | PlayStation Vita, Nintendo 3DS | 2014 | Inti Creates |
| Mighty Gunvolt Burst | Nintendo 3DS | 2017 | Inti Creates |
| Mighty Morphin Power Rangers | Super Nintendo Entertainment System | 1994 | Winning Entertainment Group |
| Mighty Morphin Power Rangers: The Fighting Edition | Super Nintendo Entertainment System | 1995 | Winning Entertainment Group |
| Mighty Morphin Power Rangers: The Movie | Super Nintendo Entertainment System, Game Boy | 1995 | Winning Entertainment Group |
| Mighty No. 9 | PlayStation Vita, Nintendo 3DS | 2016 | Inti Creates |
| Mighty Switch Force! | Nintendo 3DS | 2011 | WayForward Technologies |
| Mighty Switch Force! 2 | Nintendo 3DS | 2013 | WayForward Technologies |
| Miitopia | Nintendo 3DS | 2016 | Nintendo Entertainment Planning & Development |
| Mikeneko Homuzu no Kishido | Game Boy | 1991 | — |
| Milestone Shooting Collection 2 | Wii | 2010 | Milestone |
| Military Madness: Nectaris | Wii | 2009 | Backbone Entertainment |
| Military Multipurpose Arcade Combat Simulator | Super Nintendo Entertainment System | 1990 | — |
| Millipede | Nintendo Entertainment System | 1982 | Atari, Inc. |
| Milon's Secret Castle | Nintendo Entertainment System, Game Boy | 1986 | Hudson Soft |
| Minecraft | PlayStation Vita, Nintendo 3DS | 2011 | Mojang Studios, Microsoft |
| Minelvaton Saga: Ragon no Fukkatsu | Nintendo Entertainment System | 1987 | Random House |
| Miner 2049er | Game Boy | 1982 | Big Five Software |
| Mini Desktop Racing | Wii | 2005 | Data Design Interactive |
| Mini Golf Resort | Wii | 2010 | Rambo: The Video Game |
| Mini Ninjas | Wii | 2008 | IO Interactive |
| Mini-Putt | Nintendo Entertainment System | 1987 | Artech Digital Entertainment |
| MiniCopter: Adventure Flight | Wii | 2007 | Sonic Powered |
| Minna no Jōshikiryoku Terebi | Wii | 2008 | HAL Laboratory |
| Minon: Everyday Hero | Wii | 2007 | Red Entertainment |
| Minority Report: Everybody Runs | Nintendo GameCube | 2002 | Treyarch, Torus Games |
| Minute to Win It | Wii | 2010 | Smack Down Productions |
| Miracle Girls | Super Nintendo Entertainment System | 1993 | Now Production |
| Miracle Piano Teaching System | Nintendo Entertainment System, Super Nintendo Entertainment System | 1990 | Mindscape |
| Miracle Ropitt: 2100-Nen no Daibōken | Nintendo Entertainment System | 1987 | Micronics |
| Miracle Warriors: Seal of the Dark Lord | Nintendo Entertainment System | 1986 | Kogado Studio |
| Missile Command | Game Boy | 1980 | Atari, Inc. |
| Mission Cobra | Nintendo Entertainment System | 1990 | Thin Chen Enterprise |
| Mission: Impossible | Nintendo Entertainment System | 1990 | Konami |
| Mission: Impossible – Operation Surma | Nintendo GameCube | 2003 | Paradigm Entertainment |
| Mitsume ga Tooru | Nintendo Entertainment System | 1992 | Winning Entertainment Group |
| MLB Power Pros | Wii | 2007 | Konami |
| MLB Power Pros 2008 | Wii | 2008 | Konami |
| MLB Slugfest 20-04 | Nintendo GameCube | 2003 | — |
| MLB Slugfest 2003 | Nintendo GameCube | 2002 | — |
| MLB Superstars | Wii | 2008 | Deep Fried Entertainment |
| MLBPA Baseball | Super Nintendo Entertainment System | 1995 | — |
| Moai-kun | Nintendo Entertainment System | 1990 | Konami |
| Mobile Fighter G Gundam | Super Nintendo Entertainment System | 1994 | — |
| Mobile Suit Gundam F91: Formula Report 0122 | Super Nintendo Entertainment System | 1991 | Bandai |
| Mobile Suit Gundam: Cross Dimension 0079 | Super Nintendo Entertainment System | 1995 | Bandai |
| Mobile Suit Gundam: Gundam vs. Zeta Gundam | Nintendo GameCube | 2004 | Capcom |
| Mobile Suit Gundam: MS Sensen 0079 | Wii | 2007 | Bandai |
| Mobile Suit V Gundam | Super Nintendo Entertainment System | 1994 | — |
| Mobile Suit Z Gundam: Hot Scramble | Nintendo Entertainment System | 1986 | Game Studio |
| Moero 6!! Shin Moero!! Pro Yakyuu | Nintendo Entertainment System | 1989 | Jaleco |
| Moero 7!! Juudou Warriors | Nintendo Entertainment System | 1990 | Jaleco |
| Mohawk & Headphone Jack | Super Nintendo Entertainment System | 1996 | — |
| Mole Mania | Game Boy | 1996 | Nintendo Entertainment Analysis & Development |
| Mom-chan Diet Wii Figureobics by Jung Da-Yeon | Wii | 2010 | Mechanic Arms |
| Momoko 120% | Nintendo Entertainment System | 1986 | Jaleco |
| Momotaro Dentetsu | Nintendo Entertainment System | 1988 | Hudson Soft |
| Momotaro Dentetsu 11: Black Bombee Arrives | Nintendo GameCube | 2002 | Hudson Soft |
| Momotaro Dentetsu 12: All Aboard for Western Japan! | Nintendo GameCube | 2003 | Hudson Soft |
| Momotaro Dentetsu 16: Moving in Hokkaido! | Wii | 2007 | Hudson Soft |
| Momotaro Dentetsu 2017: Tachiagare Nippon!! | Nintendo 3DS | 2016 | — |
| Momotaro Dentetsu HAPPY | Super Nintendo Entertainment System | 1996 | — |
| Monkey Mischief: Party Time | Wii | 2008 | Nordcurrent |
| Monochrome Racing | PlayStation Vita, Wii | 2011 | Nordcurrent |
| Monopoly | Super Nintendo Entertainment System | 1992 | — |
| Monopoly | Wii | 2008 | Electronic Arts |
| Monopoly | Nintendo Entertainment System | 1991 | Sculptured Software |
| Monopoly Party! | Nintendo GameCube | 2002 | Runecraft |
| Monopoly Streets | Wii | 2010 | EA Salt Lake |
| Monsteca Corral | Wii | 2010 | Onteca (United Kingdom) |
| Monster 4x4 3D | Nintendo 3DS | 2012 | — |
| Monster 4x4: Masters of Metal | Nintendo GameCube | 2003 | Ubisoft Barcelona |
| Monster 4x4: Stunt Racer | Wii | 2009 | Ubisoft |
| Monster 4x4: World Circuit | Wii | 2006 | Ubisoft Barcelona |
| Monster High: 13 Wishes | Wii | 2013 | Game Machine Studios |
| Monster High: Ghoul Spirit | Wii | 2011 | ImaginEngine |
| Monster House | Nintendo GameCube | 2006 | Behaviour Interactive |
| Monster Hunter 3 | Wii | 2009 | Capcom |
| Monster Hunter 4 | Nintendo 3DS | 2013 | Capcom |
| Monster Hunter 4 Ultimate | Nintendo 3DS | 2014 | — |
| Monster Hunter G | Wii | 2005 | Capcom |
| Monster Hunter Generations | Nintendo 3DS | 2015 | Capcom |
| Monster Hunter Generations Ultimate | Nintendo 3DS | 2017 | — |
| Monster Hunter Stories | Nintendo 3DS | 2016 | Capcom, Marvelous |
| Monster Hunter XX | Nintendo 3DS | 2017 | Capcom |
| Monster in My Pocket | Nintendo Entertainment System | 1992 | Konami |
| Monster Jam | Wii | 2007 | Torus Games |
| Monster Jam: Maximum Destruction | Nintendo GameCube | 2002 | Inland Productions |
| Monster Jam: Path of Destruction | Wii | 2010 | Virtuos |
| Monster Jam: Urban Assault | Wii | 2008 | Torus Games |
| Monster Lab | Wii | 2008 | Backbone Entertainment |
| Monster Max | Game Boy | 1994 | Rare Ltd. |
| Monster Mayhem: Build and Battle | Wii | 2009 | Brain Toys |
| Monster Party | Nintendo Entertainment System | 1989 | Human Entertainment |
| Monster Shooter | Nintendo 3DS | 2012 | — |
| Monster Truck | Game Boy | 1990 | — |
| Monster Truck Rally | Nintendo Entertainment System | 1991 | Realtime Associates |
| Monster Truck Wars | Game Boy | 1994 | — |
| Monster Trucks Mayhem | Wii | 2009 | Zoo Corporation |
| Monster Trux Extreme: Offroad Edition | Wii | 2005 | Data Design Interactive |
| Monster Trux: Arenas | Wii | 2007 | Data Design Interactive |
| Monster Trux: Offroad | Wii | 2007 | Data Design Interactive |
| Monsters vs. Aliens | Wii | 2009 | Beenox |
| Monsters, Inc. Scream Arena | Nintendo GameCube | 2002 | Radical Entertainment |
| Moon Cresta | Super Nintendo Entertainment System | 1980 | Nichibutsu |
| Moon Crystal | Nintendo Entertainment System | 1992 | Hect |
| Moon Ranger | Nintendo Entertainment System | 1990 | Odyssey Software |
| Moonbound | Nintendo 3DS | 2021 | — |
| Mortal Kombat | Super Nintendo Entertainment System, Game Boy | 1992 | Midway Games |
| Mortal Kombat 3 | Super Nintendo Entertainment System, Game Boy | 1995 | Midway Games |
| Mortal Kombat II | Super Nintendo Entertainment System, Game Boy | 1993 | Midway Games |
| Mortal Kombat II Special | Nintendo Entertainment System | 2000 | Hummer Team |
| Mortal Kombat: Armageddon | Wii | 2006 | Midway Games |
| Mortal Kombat: Deadly Alliance | Nintendo GameCube, Game Boy | 2002 | Midway Games |
| Mortal Kombat: Deception | Nintendo GameCube | 2004 | Midway Games |
| Mother | Nintendo Entertainment System | 1989 | Nintendo |
| Motocross Maniacs | Game Boy | 1989 | Konami |
| MotoGP '08 | Wii | 2008 | Milestone S.r.l. |
| MotoHeroz | Wii | 2011 | RedLynx |
| Motoko-chan no Wonder Kitchen | Super Nintendo Entertainment System | 1993 | Nintendo |
| Motor City Patrol | Nintendo Entertainment System | 1992 | Source Research & Development |
| MotoRace USA | Nintendo Entertainment System | 1983 | Irem |
| Mountain Bike Rally | Super Nintendo Entertainment System | 1994 | Radical Entertainment |
| Mountain Sports | Wii | 2009 | Sproing Interactive Media |
| Mouse Trap Hotel | Game Boy | 1992 | Imagineering |
| Mr Bean | Wii | 2009 | Beyond Reality Games |
| Mr. Chin's Gourmet Paradise | Game Boy | 1990 | Romstar |
| Mr. Do! | Super Nintendo Entertainment System, Game Boy | 1995 | Universal Entertainment |
| Mr. Driller Drill Land | Nintendo GameCube | 2002 | Namco |
| Mr. Nutz | Super Nintendo Entertainment System | 1994 | Ocean Software |
| Mr. Tuff | Super Nintendo Entertainment System | 2023 | The Sales Curve |
| Ms. Pac-Man | Nintendo Entertainment System, Super Nintendo Entertainment System, Game Boy | 1982 | Midway Games |
| Mujintō Monogatari | Super Nintendo Entertainment System | 1994 | — |
| Multidude | Nintendo Entertainment System | 2019 | Mega Cat Studios |
| Muppet Adventure: Chaos at the Carnival | Nintendo Entertainment System | 1990 | Minds Eye Entertainment |
| Muppets Party Cruise | Nintendo GameCube | 2003 | Mass Media Inc. |
| Muramasa: The Demon Blade | PlayStation Vita, Wii | 2009 | Vanillaware |
| Murder on the Mississippi | Nintendo Entertainment System | 1986 | Activision |
| Musashi no Bōken | Nintendo Entertainment System | 1990 | Quest |
| Musashi no Ken – Tadaima Shugyō Chū | Nintendo Entertainment System | 1986 | Taito |
| Muscle Champion: Kinnikujima no Kessen | Nintendo GameCube | 2002 | Konami |
| Muscle March | Wii | 2009 | Bandai Namco Entertainment |
| Mushroom Men: The Spore Wars | Wii | 2008 | Red Fly Studio |
| Musya | Super Nintendo Entertainment System | 1992 | Jorudan |
| Mutant Fighter | Super Nintendo Entertainment System | 1992 | Data East |
| Mutant Mudds | PlayStation Vita, Nintendo 3DS | 2012 | Renegade Kid |
| Mutant Mudds Super Challenge | PlayStation Vita, Nintendo 3DS | 2016 | Renegade Kid |
| Mutsu to Nohohon | Nintendo GameCube | 2002 | Tomy |
| MVP Baseball 2004 | Nintendo GameCube | 2004 | — |
| MVP Baseball 2005 | Nintendo GameCube | 2005 | EA Vancouver |
| MX Superfly | Nintendo GameCube | 2002 | Locomotive Games |
| MX vs. ATV Untamed | Wii | 2007 | Incinerator Studios |
| My Aquarium | Wii | 2008 | Hudson Soft |
| My Aquarium 2 | Wii | 2010 | Opus Studio Inc. |
| My Baby 2 | Wii | 2009 | Dancing Dots |
| My Baby Pet Hotel 3D | Nintendo 3DS | 2013 | Independent Arts Software |
| My Baby: First Steps | Wii | 2009 | Dancing Dots |
| My Ballet Studio | Wii | 2009 | 505 Games |
| My Body Coach | Wii | 2009 | Neko Entertainment |
| My Fitness Coach | Wii | 2008 | Ubisoft |
| My Fitness Coach 2: Exercise & Nutrition | Wii | 2010 | Ubisoft |
| My French Coach and My Spanish Coach | Wii | 2007 | Sensory Sweep Studios |
| My Hero Academia: Battle for All | Nintendo 3DS | 2016 | — |
| My Horse & Me 2 | Wii | 2008 | Tate Multimedia |
| My Horse and Me | Wii | 2007 | W!Games |
| My Life My Love: Boku no Yume: Watashi no Negai | Nintendo Entertainment System | 1991 | Winkysoft |
| My Nintendo Picross: The Legend of Zelda: Twilight Princess | Nintendo 3DS | 2016 | — |
| My Pokémon Ranch | Wii | 2008 | Ambrella |
| My Style Studio: Hair Salon | Nintendo 3DS | 2013 | Cypronia |
| My Vet Practice | Wii | 2008 | Sproing Interactive Media, Neopica |
| My Word Coach | Wii | 2007 | Ubisoft Montreal |
| MySims | Wii | 2007 | Visceral Games, Tose Co., Babaroga |
| MySims Agents | Wii | 2009 | Visceral Games, Tose Co. |
| MySims Kingdom | Wii | 2008 | Visceral Games, Tose Co. |
| MySims Party | Wii | 2009 | Hudson Soft, Visceral Games |
| MySims Racing | Wii | 2009 | Behaviour Interactive |
| MySims SkyHeroes | Wii | 2010 | Behaviour Interactive |
| Myst | Nintendo 3DS | 1993 | Cyan Worlds |
| Mysterium | Game Boy | — | Maxis |
| Mystery Case Files: Dire Grove | Nintendo 3DS | 2009 | Big Fish Games |
| Mystery Case Files: Return to Ravenhearst | Nintendo 3DS | 2008 | Big Fish Games |
| Mystery Case Files: The Malgrave Incident | Wii | 2011 | Big Fish Games |
| Mystery Circle | Super Nintendo Entertainment System | 1992 | — |
| Mystery Dungeon: Shiren the Wanderer | Super Nintendo Entertainment System, Game Boy | 1995 | Chunsoft |
| Mystery Quest | Nintendo Entertainment System | 1987 | Carry Lab |
| Mystery Tower | Nintendo Entertainment System | 1986 | Namco |
| Mystic Ark | Super Nintendo Entertainment System | 1995 | Produce! |
| Mystic Heroes | Nintendo GameCube | 2002 | Koei |
| Mystical Ninja Starring Goemon | Game Boy | 1997 | Konami |
| Myth Makers: Orbs of Doom | Wii | 2007 | Data Design Interactive |
| Myth Makers: Super Kart GP | Wii | 2006 | Data Design Interactive |
| Myth Makers: Trixie in Toyland | Wii | 2005 | Data Design Interactive |
| Märchen Adventure Cotton 100% | Super Nintendo Entertainment System | 1994 | Success |
| Mōko Densetsu 95: Hanshin Tigers | Super Nintendo Entertainment System | 1995 | — |
| Mōryō Senki Madara 2 | Super Nintendo Entertainment System | 1993 | Konami |