| Q Boy | Nintendo Entertainment System | 1994 | — |
| Q*bert | Nintendo Entertainment System, Game Boy, PlayStation Vita | 1982 | Atari |
| Q*bert 3 | Super Nintendo Entertainment System | 1992 | — |
| Q11291114 | Nintendo 3DS | 2017 | — |
| Q11335621 | Nintendo 3DS | 2013 | — |
| Q131426135 | Nintendo 3DS | 2018 | — |
| Q136655558 | Nintendo Entertainment System | 1988 | GameTek |
| Q136655576 | Nintendo Entertainment System | 1990 | GameTek |
| Q136702107 | Nintendo Entertainment System | 1992 | Ocean Software |
| Q141608067 | Nintendo 3DS | 2013 | Alchemist |
| Q15875495 | Game Boy | 1992 | — |
| Q17211177 | Nintendo 3DS | 2013 | — |
| Q17211187 | Nintendo 3DS | 2014 | — |
| Q17214683 | Nintendo 3DS | 2013 | — |
| Q17214744 | Nintendo 3DS | 2013 | — |
| Q17220972 | Nintendo 3DS | 2013 | — |
| Q18339159 | Nintendo 3DS | — | SmileBoom |
| Q3835890 | Nintendo 3DS | 2011 | — |
| Q4474402 | Nintendo 3DS | 2013 | — |
| Q65228476 | Game Boy | 1994 | — |
| Q65261320 | Nintendo 3DS | 2016 | — |
| Q84763790 | Nintendo 3DS | 2015 | — |
| Q86699163 | Nintendo 3DS | 2012 | — |
| QBillion | Game Boy | 1989 | SETA Corporation |
| Qix | Nintendo Entertainment System, Game Boy | 1981 | Taito |
| Quarters, Please! | Nintendo 3DS | 2019 | Nostatic Software |
| Quarters, Please! Vol. 2 | Nintendo 3DS | 2020 | Nostatic Software |
| Quattro Adventure | Nintendo Entertainment System | 1993 | — |
| Quattro Sports | Nintendo Entertainment System | 1993 | — |
| Quell Memento | Nintendo 3DS | 2015 | — |
| Quell Reflect | Nintendo 3DS | 2011 | — |
| Quest of Dungeons | Nintendo 3DS | 2014 | — |
| Quiz Party | Wii | 2012 | Wizarbox |