| Mappy-Land | Nintendo Entertainment System | 1986 | Tose Co. |
| Marble Madness | Nintendo Entertainment System, Game Boy | 1984 | Atari Games |
| Marble Saga: Kororinpa | Wii | 2009 | Hudson Soft |
| Margot's Word Brain | Wii | 2008 | Slam Games |
| Marines: Modern Urban Combat | Wii | 2009 | Destineer |
| Mario & Luigi: Bowser's Inside Story + Bowser Jr.'s Journey | Nintendo 3DS | 2018 | — |
| Mario & Luigi: Dream Team | Nintendo 3DS | 2013 | AlphaDream |
| Mario & Luigi: Paper Jam | Nintendo 3DS | 2015 | AlphaDream |
| Mario & Luigi: Superstar Saga + Bowser's Minions | Nintendo 3DS | 2017 | — |
| Mario & Sonic at the London 2012 Olympic Games | Nintendo 3DS, Wii | 2011 | Sega Sports R&D |
| Mario & Sonic at the Olympic Games | Wii | 2007 | Sega Sports R&D |
| Mario & Sonic at the Olympic Winter Games | Wii | 2009 | Sonic Team, Racjin |
| Mario & Sonic at the Rio 2016 Olympic Games | Nintendo 3DS | 2016 | Sega Sports R&D |
| Mario & Wario | Super Nintendo Entertainment System | 1993 | Game Freak |
| Mario and Donkey Kong: Minis on the Move | Nintendo 3DS | 2013 | Nintendo Software Technology |
| Mario Bros. | Nintendo Entertainment System | 1984 | Nintendo |
| Mario Golf: Toadstool Tour | Nintendo GameCube | 2003 | Camelot Software Planning |
| Mario Golf: World Tour | Nintendo 3DS | 2014 | Camelot Software Planning |
| Mario Is Missing! | Nintendo Entertainment System, Super Nintendo Entertainment System | 1993 | The Software Toolworks |
| Mario Kart 7 | Nintendo 3DS | 2011 | Nintendo Entertainment Analysis & Development, Retro Studios |
| Mario Kart Wii | Wii | 2008 | Nintendo Entertainment Analysis & Development |
| Mario Kart: Double Dash | Nintendo GameCube | 2003 | Nintendo Entertainment Analysis & Development |
| Mario Paint | Super Nintendo Entertainment System | 1992 | Nintendo Research & Development 1 |
| Mario Party 4 | Nintendo GameCube | 2002 | Hudson Soft |
| Mario Party 5 | Nintendo GameCube | 2003 | Hudson Soft |
| Mario Party 6 | Nintendo GameCube | 2004 | Hudson Soft |
| Mario Party 7 | Nintendo GameCube | 2005 | Hudson Soft |
| Mario Party 8 | Wii | 2007 | Hudson Soft |
| Mario Party 9 | Wii | 2012 | Nintendo Cube |
| Mario Party: Island Tour | Nintendo 3DS | 2013 | Nintendo Cube |
| Mario Party: Star Rush | Nintendo 3DS | 2016 | Nintendo Cube |
| Mario Party: The Top 100 | Nintendo 3DS | 2017 | Nintendo Cube |
| Mario Power Tennis | Nintendo GameCube, Wii | 2004 | Camelot Software Planning |
| Mario Sports Mix | Wii | 2010 | Square Enix |
| Mario Sports Superstars | Nintendo 3DS | 2017 | Bandai Namco Entertainment |
| Mario Strikers Charged | Wii | 2007 | Next Level Games |
| Mario Super Sluggers | Wii | 2008 | Bandai Namco Entertainment |
| Mario Superstar Baseball | Nintendo GameCube | 2005 | Namco |
| Mario Tennis Open | Nintendo 3DS | 2012 | Camelot Software Planning |
| Mario vs. Donkey Kong: Tipping Stars | Nintendo 3DS | 2015 | Nintendo Software Technology |
| Mario's Early Years! Fun with Letters | Super Nintendo Entertainment System | 1993 | — |
| Mario's Early Years! Fun with Numbers | Super Nintendo Entertainment System | 1994 | — |
| Mario's Early Years! Preschool Fun | Super Nintendo Entertainment System | 1994 | — |
| Mario's Picross | Super Nintendo Entertainment System, Game Boy | 1995 | Ape, Inc., Jupiter |
| Mario's Super Picross | Super Nintendo Entertainment System | 1995 | Creatures |
| Mario's Time Machine | Nintendo Entertainment System, Super Nintendo Entertainment System | 1993 | Mindscape |
| Mark Davis Pro Bass Challenge | Nintendo GameCube | 2003 | SIMS Co., Ltd. |
| Mark Davis' The Fishing Master | Super Nintendo Entertainment System | 1995 | Winning Entertainment Group |
| Mart Racer | Wii | 2009 | Joju Games |
| Martian Panic | Wii | 2010 | N-Fusion Interactive |
| Maru's Mission | Game Boy | 1990 | Tose Co. |
| Marvel Land | Wii | 1990 | Namco |
| Marvel Nemesis: Rise of the Imperfects | Nintendo GameCube | 2005 | nStigate Games |
| Marvel Super Hero Squad | Wii | 2009 | Blue Tongue Entertainment |
| Marvel Super Hero Squad: Comic Combat | Wii | 2011 | Griptonite Games |
| Marvel Super Hero Squad: The Infinity Gauntlet | Wii | 2010 | Griptonite Games |
| Marvel Super Heroes 3D: Grandmaster's Challenge | Wii | 2010 | Neko Entertainment |
| Marvel Super Heroes in War of the Gems | Super Nintendo Entertainment System | 1996 | Capcom |
| Marvel: Ultimate Alliance | Wii | 2006 | Raven Software |
| Marvel: Ultimate Alliance 2 | Wii | 2009 | Blizzard Albany |