| Tiki Towers | Wii | 2008 | Mock Science |
| Time Diver: Eon Man | Nintendo Entertainment System | — | Atlus |
| Time Lord | Nintendo Entertainment System | 1990 | Rare Ltd. |
| Time Slip | Super Nintendo Entertainment System | 1993 | Eidos Interactive |
| Time Trax | Super Nintendo Entertainment System | 1994 | — |
| Timeball | Game Boy | 1984 | Hudson Soft |
| Timecop | Super Nintendo Entertainment System | 1995 | Cryo Interactive |
| Times of Lore | Nintendo Entertainment System | 1988 | Origin Systems |
| TimeSplitters 2 | Nintendo GameCube | 2002 | Crytek UK |
| TimeSplitters: Future Perfect | Nintendo GameCube | 2005 | Crytek UK |
| Timon & Pumbaa's Jungle Games | Super Nintendo Entertainment System | 1995 | 7th Level, Tiertex Design Studios |
| Tin Star | Super Nintendo Entertainment System | 1994 | Software Creations |
| Tintin in Tibet | Super Nintendo Entertainment System | 1995 | Infogrames |
| Tintin: Le Temple du Soleil | Game Boy | 1996 | — |
| Tiny Toon Adventures | Nintendo Entertainment System | 1991 | Konami |
| Tiny Toon Adventures 2: Montana's Movie Madness | Game Boy | 1993 | Konami |
| Tiny Toon Adventures 2: Trouble in Wackyland | Nintendo Entertainment System | 1992 | Konami |
| Tiny Toon Adventures 6 | Nintendo Entertainment System | 1997 | Hummer Team |
| Tiny Toon Adventures Cartoon Workshop | Nintendo Entertainment System | 1992 | Appaloosa Interactive |
| Tiny Toon Adventures: Babs' Big Break | Game Boy | 1992 | Konami |
| Tiny Toon Adventures: Buster Busts Loose! | Super Nintendo Entertainment System | 1992 | Konami |
| Tiny Toon Adventures: Wacky Sports Challenge | Super Nintendo Entertainment System | 1994 | Konami |
| Titus the Fox | Game Boy | 1991 | Titus Interactive |
| TKO Super Championship Boxing | Super Nintendo Entertainment System | 1992 | Sting |
| TM Network: Live in Power Bowl | Nintendo Entertainment System | 1989 | Sony Music Entertainment Japan |
| TMNT | Nintendo GameCube, Wii | 2007 | Ubisoft Quebec |
| TNA Impact! | Wii | 2008 | Midway Studios – Los Angeles |
| TNN Bass Tournament of Champions | Super Nintendo Entertainment System | 1994 | ASC Games |
| TNT Racers | Wii | 2010 | DTP entertainment |
| To the Earth | Nintendo Entertainment System | 1989 | Cirque Verte |
| Todd McFarlane's Spawn: The Video Game | Super Nintendo Entertainment System | — | Ukiyotei |
| Toki | Nintendo Entertainment System | 1989 | TAD Corporation |
| Toki no Tabibito -Time Stranger- | Nintendo Entertainment System | 1986 | Kemco |
| Toki Tori | Wii | 2001 | Two Tribes |
| Toki Tori 3D | Nintendo 3DS | 2015 | Two Tribes |
| Tokimeki Memorial | Super Nintendo Entertainment System | 1994 | Konami |
| Tokyo City Nights | Wii | 2008 | Gameloft |
| Tokyo Crash Mobs | Nintendo 3DS | 2013 | Mitchell Corporation |
| Tokyo Disneyland: Mickey no Cinderella Shiro Mystery Tour | Game Boy | 1995 | — |
| Tom & Jerry | Nintendo Entertainment System | 1991 | Software Creations |
| Tom & Jerry | Super Nintendo Entertainment System | 1993 | — |
| Tom & Jerry | Game Boy | 1992 | — |
| Tom and Jerry in War of the Whiskers | Nintendo GameCube | 2002 | VIS Entertainment |
| Tom and Jerry: Frantic Antics | Game Boy | 1993 | Krome Studios Melbourne |
| Tom Clancy's Ghost Recon | Nintendo GameCube | 2001 | Red Storm Entertainment |
| Tom Clancy's Ghost Recon | Wii | 2010 | Next Level Games |
| Tom Clancy's Ghost Recon 2 | Nintendo GameCube | 2004 | Red Storm Entertainment |
| Tom Clancy's Ghost Recon: Future Soldier | Wii | 2012 | Ubisoft Paris |
| Tom Clancy's Ghost Recon: Shadow Wars | Nintendo 3DS | 2011 | Ubisoft |
| Tom Clancy's H.A.W.X 2 | Wii | 2010 | Ubisoft Romania |
| Tom Clancy's Rainbow Six 3: Raven Shield | Nintendo GameCube | 2003 | Ubisoft Milan, Red Storm Entertainment, Ubisoft Montreal |
| Tom Clancy's Rainbow Six: Lockdown | Nintendo GameCube | 2005 | Red Storm Entertainment |
| Tom Clancy's Splinter Cell | Nintendo GameCube | 2002 | Ubisoft Montreal |
| Tom Clancy's Splinter Cell 3D | Nintendo 3DS | 2011 | — |
| Tom Clancy's Splinter Cell: Chaos Theory | Nintendo GameCube | 2005 | Ubisoft |
| Tom Clancy's Splinter Cell: Double Agent | Nintendo GameCube, Wii | 2006 | Ubisoft Shanghai |
| Tom Clancy's Splinter Cell: Pandora Tomorrow | Nintendo GameCube | 2004 | Ubisoft Shanghai |
| Tomb Raider: Anniversary | Wii | 2007 | Crystal Dynamics |
| Tomb Raider: Legend | Nintendo GameCube | 2006 | Crystal Dynamics |
| Tomb Raider: Underworld | Wii | 2008 | Crystal Dynamics |