| TrackMania | Wii | 2010 | Nadeo |
| Transformers: Cybertron Adventures | Wii | 2010 | Next Level Games |
| Transformers: Dark of the Moon | Wii | 2011 | High Moon Studios |
| Transformers: Prime – The Game | Wii | 2012 | Now Production |
| Transformers: Revenge of the Fallen | Wii | 2009 | Luxoflux |
| Transformers: Rise of the Dark Spark | Nintendo 3DS | 2014 | Edge of Reality |
| Transformers: The Game | Wii | 2007 | Traveller's Tales |
| Transworld Surf | Nintendo GameCube | 2001 | Rockstar San Diego |
| Trauma Center: New Blood | Wii | 2007 | Atlus |
| Trauma Center: Second Opinion | Wii | 2006 | Atlus |
| Trauma Team | Wii | 2010 | Atlus |
| Traverse: Starlight & Prairie | Super Nintendo Entertainment System | 1996 | — |
| Trax | Game Boy | 1991 | HAL Laboratory |
| Treasure Hunter G | Super Nintendo Entertainment System | 1996 | Sting |
| Treasure Master | Nintendo Entertainment System | 1991 | Software Creations |
| Treasure of the Rudras | Super Nintendo Entertainment System | 1996 | Square |
| Trials of Mana | Super Nintendo Entertainment System | 1995 | Square |
| Trigger Man | Nintendo GameCube | 2004 | Point of View, Inc. |
| Trip World | Game Boy | 1992 | Sunsoft |
| Trivial Pursuit | Wii | 2009 | EA Bright Light |
| Troddlers | Super Nintendo Entertainment System | 1992 | Atod |
| Trog | Nintendo Entertainment System | 1990 | Midway Games |
| Trojan | Nintendo Entertainment System | 1986 | Capcom |
| Tron Evolution: Battle Grids | Wii | 2010 | n-Space |
| Tron: Evolution | Wii | 2010 | Propaganda Games |
| Troy Aikman NFL Football | Super Nintendo Entertainment System | 1995 | Leland Interactive Media |
| True Crime: New York City | Nintendo GameCube | 2005 | Luxoflux |
| True Crime: Streets of LA | Nintendo GameCube | 2003 | Luxoflux |
| True Golf Classics: Pebble Beach Golf Links | Super Nintendo Entertainment System | 1992 | D Wonderland Inc. |
| True Golf Classics: Waialae Country Club | Super Nintendo Entertainment System | 1992 | D Wonderland Inc. |
| True Golf Classics: Wicked 18 | Super Nintendo Entertainment System | 1993 | D Wonderland Inc. |
| True Lies | Super Nintendo Entertainment System | 1994 | Krome Studios Melbourne |
| Trump Boy | Game Boy | — | Pack-In-Video |
| Trump Boy II | Game Boy | 1990 | Pack-In-Video |
| Truth or Lies | Wii | 2010 | Big Ant Studios |
| Tsukikomori | Super Nintendo Entertainment System | 1996 | — |
| Tsuppari Wars | Nintendo Entertainment System | 1991 | Sega Sammy Holdings, Sammy Corporation |
| Tsuppari Ōzumō: Risshin Shusse Hen | Super Nintendo Entertainment System | 1993 | — |
| Tsurupika Hagemaru Mezase! Tsuru Seko no Akashi | Nintendo Entertainment System | 1991 | Jaleco |
| Tsuyoshi Shikkari Shinasai: Taisen Puzzle-dama | Super Nintendo Entertainment System | 1994 | — |
| Tsūshin Taikyoku: Hayazashi Shogi Sandan | Wii | 2008 | Nintendo Entertainment System |
| Tsūshin Taikyoku: Igo Dōjō 2700-Mon | Wii | 2008 | Spice Games, Southern Create |
| Tube Slider | Nintendo GameCube | 2003 | Nintendo Cube |
| Tuff E Nuff | Super Nintendo Entertainment System | 1993 | Jaleco |
| Tumblebugs | Wii | 2005 | Wildfire Studios |
| Turn and Burn: No-Fly Zone | Super Nintendo Entertainment System | 1994 | Imagineering |
| Turn and Burn: The F-14 Dogfight Simulator | Game Boy | 1992 | Imagineering |
| Turnabout Reclaimed | Nintendo 3DS | 2013 | — |
| Turnabout Time Traveler | Nintendo 3DS | 2016 | — |
| Turok: Battle of the Bionosaurs | Game Boy | 1997 | Bit Managers |
| Turok: Evolution | Nintendo GameCube | 2002 | RFX Interactive |
| Turrican | Game Boy | 1990 | Rainbow Arts, Factor 5 |
| Turtle Tale | Nintendo 3DS | — | Saturnine Games |
| TV Champion | Game Boy | 1994 | — |
| TV no Tomo Channel | Wii | 2008 | Nintendo |
| TV Show King | Wii | 2008 | Gameloft |
| TV Show King 2 | Wii | 2009 | Gameloft |
| TV Show King Party | Wii | 2008 | Gameloft |
| Twin Cobra | Nintendo Entertainment System | 1987 | Bitwave Games, A.I Co., Ltd., Toaplan, Micronics |
| Twin Eagle | Nintendo Entertainment System | 1988 | SETA Corporation |