| The Mask | Super Nintendo Entertainment System | 1995 | — |
| The Minna de Kart Race | Wii | 2007 | Tose Co. |
| The Money Game | Nintendo Entertainment System | 1988 | SOFEL |
| The Monkey King: The Legend Begins | Wii | 2007 | OperaHouse |
| The Monopoly Game 2 | Super Nintendo Entertainment System | 1995 | — |
| The Mummy: Tomb of the Dragon Emperor | Wii | 2008 | Eurocom |
| The Munchables | Wii | 2009 | Bandai Namco Holdings |
| The Mutant Virus: Crisis in a Computer World | Nintendo Entertainment System | 1992 | Rocket Science Games |
| The Naked Brothers Band The Video Game | Wii | 2008 | Barking Lizards Technologies |
| The NewZealand Story | Nintendo Entertainment System | 1988 | Taito |
| The Ninja Warriors | Super Nintendo Entertainment System | 1994 | Winning Entertainment Group |
| The Oregon Trail | Wii | 2011 | SVG Distribution |
| The P'Radikus Conflict | Nintendo Entertainment System | — | Color Dreams |
| The Pagemaster | Super Nintendo Entertainment System | 1994 | Acclaim Studios London |
| The Parallel of Haruhi Suzumiya | Wii | 2009 | Cavia |
| The Party Game | Wii | 2008 | Tamsoft |
| The Peace Keepers | Super Nintendo Entertainment System | 1993 | Jaleco |
| The Peanuts Movie: Snoopy's Grand Adventure | Nintendo 3DS | 2015 | Beenox |
| The Penguins of Madagascar: Dr. Blowhole Returns – Again! | Wii | 2011 | Griptonite Games |
| The Pirates of Dark Water | Super Nintendo Entertainment System | 1994 | Acclaim Studios Austin |
| The Polar Express | Nintendo GameCube | 2004 | Blue Tongue Entertainment |
| The Portopia Serial Murder Case | Nintendo Entertainment System | 1983 | Yuji Horii |
| The Powerpuff Girls: Relish Rampage | Nintendo GameCube | 2002 | High Voltage Software |
| The Price Is Right | Wii | 2008 | Ludia |
| The Price Is Right: 2010 Edition | Wii | 2009 | Ludia |
| The Princess and the Frog | Wii | 2009 | Griptonite Games |
| The Punisher | Nintendo Entertainment System, Game Boy | 1990 | Krome Studios Melbourne |
| The Quest of Ki | Nintendo Entertainment System | 1988 | Game Studio |
| The Real Ghostbusters | Game Boy | 1993 | Kemco |
| The Ren & Stimpy Show: Buckaroo$! | Nintendo Entertainment System, Super Nintendo Entertainment System | 1993 | Imagineering |
| The Ren & Stimpy Show: Fire Dogs | Super Nintendo Entertainment System | — | Argonaut Games |
| The Ren & Stimpy Show: Time Warp | Super Nintendo Entertainment System | 1994 | — |
| The Ren & Stimpy Show: Veediots! | Super Nintendo Entertainment System | 1993 | — |
| The Rescue of Princess Blobette | Game Boy | 1990 | Imagineering |
| The Rocketeer | Nintendo Entertainment System | 1991 | Realtime Associates |
| The Rugrats Movie | Game Boy | 1999 | Software Creations |
| The Scorpion King: Rise of the Akkadian | Nintendo GameCube | 2002 | Point of View, Inc. |
| The Secret Saturdays: Beasts of the 5th Sun | Wii | 2009 | High Voltage Software |
| The Seven Deadly Sins: Unjust Sin | Nintendo 3DS | 2015 | — |
| The Shadow | Super Nintendo Entertainment System | 1994 | Ocean Software |
| The Shinri Game 2 | Super Nintendo Entertainment System | 1995 | — |
| The Simpsons Game | Wii | 2007 | Celbridge |
| The Simpsons: Bart & the Beanstalk | Game Boy | 1994 | Software Creations |
| The Simpsons: Bart vs. the Juggernauts | Game Boy | 1992 | Imagineering |
| The Simpsons: Bart vs. the Space Mutants | Nintendo Entertainment System | 1991 | Imagineering |
| The Simpsons: Bart vs. the World | Nintendo Entertainment System | 1991 | Imagineering |
| The Simpsons: Bart's Nightmare | Super Nintendo Entertainment System | 1992 | Sculptured Software |
| The Simpsons: Bartman Meets Radioactive Man | Nintendo Entertainment System | 1992 | Imagineering |
| The Simpsons: Hit & Run | Nintendo GameCube | 2003 | Radical Entertainment |
| The Simpsons: Itchy & Scratchy in Miniature Golf Madness | Game Boy | 1993 | Krome Studios Melbourne |
| The Simpsons: Road Rage | Nintendo GameCube | 2001 | Fox Interactive |
| The Sims | Nintendo GameCube | 2003 | Maxis, Edge of Reality |
| The Sims | Nintendo GameCube | 2000 | Maxis |
| The Sims 2 | Nintendo GameCube | 2004 | Maxis |
| The Sims 2 (consoles) | Nintendo GameCube | 2005 | Maxis |
| The Sims 2: Castaway | Wii | 2007 | Electronic Arts |
| The Sims 2: Pets | Nintendo GameCube, Wii | 2006 | Maxis |
| The Sims 2: Pets | Nintendo GameCube, Wii | 2006 | Visceral Games, Maxis |
| The Sims 3 | Nintendo 3DS, Wii | 2009 | The Sims Studio, Maxis, EA Mobile, Edge of Reality |
| The Sims 3 (handheld) | Nintendo 3DS | 2010 | Visceral Games, The Sims Studio, Maxis |