| Arcade Classic No. 1: Asteroids / Missile Command | Game Boy | 1995 | The Code Monkeys |
| Arcade Classic No. 2: Centipede / Millipede | Game Boy | 1995 | The Code Monkeys |
| Arcade Hits Pack: Gunblade NY & L.A. Machineguns | Wii | 2010 | Sega |
| Arcade Shooting Gallery | Wii | 2009 | CyberPlanet Interactive, CyberPlanet Interactive |
| Arcade Zone | Wii | 2009 | Activision |
| Arcade's Greatest Hits: The Atari Collection 1 | Super Nintendo Entertainment System | 1996 | Backbone Entertainment |
| Arcana | Super Nintendo Entertainment System | 1992 | HAL Laboratory |
| Arch Rivals | Nintendo Entertainment System | 1989 | Midway Games |
| Archon: The Light and the Dark | Nintendo Entertainment System | 1983 | Free Fall Associates |
| Arctic Tale | Wii | 2007 | Atomic Planet Entertainment |
| Arcus Odyssey | Super Nintendo Entertainment System | 1993 | Namco Tales Studio |
| Ardy Lightfoot | Super Nintendo Entertainment System | 1993 | ASCII Corporation |
| Are You Smarter Than a 5th Grader?: Back to School | Wii | 2010 | ImaginEngine |
| Are You Smarter Than a 5th Grader?: Game Time | Wii | 2009 | ImaginEngine |
| Are You Smarter Than a 5th Grader?: Make the Grade | Wii | 2008 | ImaginEngine |
| Aretha | Super Nintendo Entertainment System | 1993 | Japan Art Media |
| Aretha II | Game Boy | 1991 | — |
| Aretha II: Ariel no Fushigi na Tabi | Super Nintendo Entertainment System | 1994 | Game Arts, Japan Art Media |
| Argus | Nintendo Entertainment System | 1986 | NMK |
| Ark | Game Boy | 2022 | — |
| Arkanoid | Nintendo Entertainment System, Super Nintendo Entertainment System, Wii | 1986 | Taito |
| Arkanoid Plus! | Wii | 2009 | Taito |
| Arkanoid: Doh It Again | Super Nintendo Entertainment System | 1997 | Taito |
| Arkanoid: Revenge of Doh | Nintendo Entertainment System | 1987 | Taito |
| Arkista's Ring | Nintendo Entertainment System | 1990 | NMK, Sammy Corporation |
| Armadillo | Nintendo Entertainment System | 1991 | Fortyfive |
| Armin van Buuren: In the Mix | Wii | 2010 | Findev |
| Armored Police Metal Jack | Game Boy | 1992 | KID |
| Armored Police Metal Jack | Super Nintendo Entertainment System | 1992 | — |
| Army Men: Air Attack 2 | Nintendo GameCube | 2000 | The 3DO Company |
| Army Men: Air Combat - The Elite Missions | Nintendo GameCube | 2003 | — |
| Army Men: RTS | Nintendo GameCube | 2002 | Pandemic Studios |
| Army Men: Sarge's War | Nintendo GameCube | 2004 | 2K Play |
| Army Men: Soldiers of Misfortune | Wii | 2008 | Big Blue Bubble |
| Art Academy: Lessons for Everyone! | Nintendo 3DS | 2012 | Kuju Ltd. |
| Art of Balance TOUCH! | Nintendo 3DS | 2012 | — |
| Art of Fighting 2 | Super Nintendo Entertainment System | 1994 | SNK |
| Artelius | Nintendo Entertainment System | 1987 | Nichibutsu |
| Arthur and the Revenge of Maltazard | Wii | 2010 | Ubisoft |
| Asameshimae Nyanko | Super Nintendo Entertainment System | 1994 | — |
| Asdivine Cross | Nintendo 3DS | 2021 | Exe-Create |
| Ash | Nintendo 3DS | 2010 | — |
| Ashes Cricket 2009 | Wii | 2009 | Transmission Games |
| Ashita no Joe | Super Nintendo Entertainment System | 1992 | — |
| Asmik-kun Land | Nintendo Entertainment System | 1991 | Graphic Research Co., Ltd. |
| Asmik-kun World 2 | Game Boy | 1991 | — |
| Asphalt 3D | Nintendo 3DS | 2011 | Gameloft |
| Assassin's Creed: Lost Legacy | Nintendo 3DS | — | Ubisoft |
| Assassination Classroom: Assassin Training Plan | Nintendo 3DS | 2016 | — |
| Assassination Classroom: Grand Siege on Korosensei | Nintendo 3DS | 2015 | — |
| Assault Suits Valken 2 | Super Nintendo Entertainment System | 1992 | Nippon Computer Systems |
| Asteka II: Templo del Sol | Nintendo Entertainment System | 1986 | Nihon Falcom |
| Asterix | Nintendo Entertainment System, Super Nintendo Entertainment System, Game Boy | 1993 | Bit Managers |
| Asterix & Obelix | Super Nintendo Entertainment System | 1995 | Bit Managers |
| Asterix & Obelix XXL | Nintendo GameCube | 2004 | Étranges Libellules |
| Asterix at the Olympic Games | Wii | 2007 | Étranges Libellules |
| Astral Bout | Super Nintendo Entertainment System | 1992 | — |
| Astro Boy: The Video Game | Wii | 2009 | High Voltage Software |
| Astro Fang: Super Machine | Nintendo Entertainment System | 1990 | Soft Machine |
| Astro Rabby | Game Boy | 1990 | — |