| Athena | Nintendo Entertainment System | 1986 | SNK |
| Athletic World | Game Boy | 2023 | — |
| Athletic World | Nintendo Entertainment System | 1986 | Human Entertainment |
| Atlantic Quest | Nintendo 3DS | 2014 | — |
| Atlantis no Nazo | Nintendo Entertainment System | 1986 | Sunsoft |
| Atomic Punk | Game Boy | 1990 | Hudson Soft |
| Atrévete a Soñar | Wii | 2010 | Grupo Televisa |
| Attack Animal Gakuen | Nintendo Entertainment System | 1987 | Scitron & Art Inc. |
| Attack of the Friday Monsters! A Tokyo Tale | Nintendo 3DS | 2013 | Aquria, Millennium Kitchen |
| Attack of the Killer Tomatoes | Nintendo Entertainment System, Game Boy | 1991 | Imagineering |
| Attack of the Movies 3D | Wii | 2010 | Panic Button |
| Attack on Titan: Escape from Certain Death | Nintendo 3DS | 2017 | Koei Tecmo Holdings |
| Attack on Titan: Humanity in Chains | Nintendo 3DS | 2013 | Spike Chunsoft |
| ATV Quad Power Racing 2 | Nintendo GameCube | 2003 | Black Rock Studio |
| ATV: Quad Kings | Wii | 2009 | Beyond Reality Games |
| Aussie Rules Footy | Nintendo Entertainment System | 1991 | Krome Studios Melbourne |
| Auto Modellista | Nintendo GameCube | 2002 | Capcom |
| Avatar: The Last Airbender | Nintendo GameCube, Wii | 2006 | Tose Co., Halfbrick Studios, THQ Studio Australia |
| Avatar: The Last Airbender – Into the Inferno | Wii | 2008 | Nickelodeon |
| Avatar: The Last Airbender – The Burning Earth | Wii | 2007 | THQ |
| Axelay | Super Nintendo Entertainment System | 1992 | Konami |
| Ayakashi no Shiro | Game Boy | 1990 | — |
| Azure Snake | Nintendo 3DS | 2019 | RandomSpin Games |
| Azure Striker Gunvolt | Nintendo 3DS | 2014 | Inti Creates |
| Azure Striker Gunvolt 2 | Nintendo 3DS | 2016 | Inti Creates |
| Azure Striker Gunvolt: Striker Pack | Nintendo 3DS | 2016 | — |
| B-Wings | Nintendo Entertainment System | 1984 | Data East |
| B.O.B. | Super Nintendo Entertainment System | 1993 | — |
| Baby Boomer | Nintendo Entertainment System | 1989 | Color Dreams |
| Babysitting Mama | Wii | 2010 | Cooking Mama Limited |
| Back to the Future | Nintendo Entertainment System | 1989 | Krome Studios Melbourne |
| Back to the Future Part II & III | Nintendo Entertainment System | 1990 | Krome Studios Melbourne |
| Back to the Future: The Game | Wii | 2010 | Telltale Games |
| Backyard Baseball | Nintendo GameCube | 2003 | — |
| Backyard Baseball '09 | Wii | 2008 | FarSight Studios |
| Backyard Baseball '10 | Wii | 2009 | FarSight Studios |
| Backyard Baseball 2007 | Nintendo GameCube | 2007 | — |
| Backyard Football | Nintendo GameCube | 2002 | — |
| Backyard Football '08 | Wii | 2007 | Humongous Entertainment |
| Backyard Football '09 | Wii | 2008 | Humongous Entertainment |
| Backyard Football '10 | Wii | 2009 | Humongous Entertainment |
| Backyard Sports: Rookie Rush | Wii | 2010 | Humongous Entertainment |
| Backyard Sports: Sandlot Sluggers | Wii | 2010 | HB Studios, Powerhead Games |
| Bad Boys: Miami Takedown | Nintendo GameCube | 2004 | Blitz Games |
| Bad Dudes Vs. DragonNinja | Nintendo Entertainment System | 1988 | Data East |
| Bad News Baseball | Nintendo Entertainment System | 1989 | Tecmo |
| Bad Street Brawler | Nintendo Entertainment System | 1987 | Krome Studios Melbourne |
| Baddest of the Bands | Wii | 2008 | Telltale Games |
| Bahamut Lagoon | Super Nintendo Entertainment System | 1996 | Square |
| Baja Mania | Wii | — | Broadsword Interactive Limited |
| Bakugan Battle Brawlers | Wii | 2009 | Now Production |
| Bakugan: Defenders of the Core | Wii | 2010 | Now Production |
| Bakushou!! Kinsey Gekijou | Nintendo Entertainment System, Super Nintendo Entertainment System | 1989 | Taito |
| Bakushō! Ai no Gekijō | Nintendo Entertainment System | 1990 | Coconuts Japan |
| Bakushō! Star Monomane Shitennō | Nintendo Entertainment System | 1990 | Pack-In-Video |
| Baldur's Gate: Dark Alliance | Nintendo GameCube | 2001 | High Voltage Software, Snowblind Studios |
| Ball Bullet Gun: Survival Game Simulation | Super Nintendo Entertainment System | 1995 | — |
| Ballblazer | Nintendo Entertainment System | 1984 | Lucasfilm Games |
| Balloon Fight | Nintendo Entertainment System, Nintendo GameCube, Nintendo 3DS, Wii | 1984 | HAL Laboratory, Nintendo Research & Development 1 |
| Balloon Kid | Nintendo Entertainment System, Game Boy, Nintendo 3DS | 1990 | Nintendo Research & Development 1 |