| Chicken Blaster | Wii | 2009 | indiePub |
| Chicken Little | Nintendo GameCube | 2005 | Avalanche Software |
| Chicken Riot | Wii | 2009 | CI Games S.A. |
| Chicken Shoot | Wii | 2007 | Destination Software Inc. |
| Chicken Wiggle | Nintendo 3DS | 2017 | Atooi |
| Chikyū Kaihō Gun ZAS | Game Boy | 1992 | D Wonderland Inc. |
| Chiller | Nintendo Entertainment System | 1985 | — |
| Chiller | Nintendo Entertainment System | 1986 | Exidy |
| Chinese Chess | Nintendo Entertainment System | 1991 | Micro Genius |
| Chip 'n Dale Rescue Rangers | Nintendo Entertainment System | 1990 | Capcom |
| Chip 'n Dale Rescue Rangers 2 | Nintendo Entertainment System | 1993 | Capcom |
| Chiyonofuji no Ōichō | Nintendo Entertainment System | 1990 | Arc System Works |
| Choplifter | Nintendo Entertainment System | 1982 | Dan Gorlin |
| Choplifter II | Game Boy | 1991 | Krome Studios Melbourne |
| Choplifter III | Super Nintendo Entertainment System | 1994 | Krome Studios Melbourne |
| Chrono Resurrection | Nintendo GameCube | 2004 | — |
| Chrono Trigger | Super Nintendo Entertainment System, PlayStation Vita, Wii | 1995 | Square |
| Chrono Trigger: Crimson Echoes | Super Nintendo Entertainment System | 2009 | — |
| Chronus Arc | Nintendo 3DS | 2013 | Hit-Point |
| Chrysler Classic Racing | Wii | 2008 | Extra Mile Studios |
| Chubby Cherub | Nintendo Entertainment System | 1985 | Tose Co. |
| Chuck E. Cheese's Party Games | Wii | 2010 | UFO Interactive Games |
| Chuck E. Cheese's Sports Games | Wii | 2011 | Tommo Inc. |
| Chō Aniki: Bakuretsu Rantō-hen | Super Nintendo Entertainment System | 1995 | Masaya |
| Chūka taisen | Nintendo Entertainment System | 1988 | Taito |
| CID The Dummy | Wii | 2009 | Oxygen Games |
| Circus Caper | Nintendo Entertainment System | 1989 | Advance Communication |
| Circus Charlie | Nintendo Entertainment System | 1984 | Konami |
| Circus Games | Wii | 2008 | 505 Games |
| Citizens of Earth | PlayStation Vita, Nintendo 3DS | 2015 | Eden Industries |
| City Builder | Wii | 2010 | Collision Studios |
| City Connection | Nintendo Entertainment System | 1985 | Jaleco, Aackosoft |
| Civilization | Super Nintendo Entertainment System | 1991 | MicroProse |
| Clash at Demonhead | Nintendo Entertainment System | 1989 | Tokai Communications |
| Classic British Motor Racing | Wii | 2008 | Data Design Interactive |
| Classic Concentration | Nintendo Entertainment System | 1988 | Softie |
| Classic Road | Super Nintendo Entertainment System | 1993 | — |
| Classic Road II | Super Nintendo Entertainment System | 1995 | — |
| ClayFighter | Super Nintendo Entertainment System | 1993 | Visual Concepts |
| ClayFighter 2: Judgment Clay | Super Nintendo Entertainment System | 1995 | Interplay Entertainment |
| Claymates | Super Nintendo Entertainment System | 1993 | Visual Concepts |
| Cliffhanger | Nintendo Entertainment System, Super Nintendo Entertainment System, Game Boy | 1993 | Rockstar Lincoln |
| Clock Tower | Super Nintendo Entertainment System | 1995 | Human Entertainment |
| ClockWerx | Super Nintendo Entertainment System | 1995 | Callisto Corporation |
| Cloudy with a Chance of Meatballs | Wii | 2009 | Sony Interactive Entertainment |
| Clu Clu Land | Nintendo Entertainment System, Nintendo 3DS, Wii | 1984 | Nintendo Research & Development 1 |
| Club Penguin: Game Day! | Wii | 2010 | Artoon |
| Clue | Super Nintendo Entertainment System | 1992 | Sculptured Software |
| Coaster Creator 3D | Nintendo 3DS | 2013 | — |
| Cobra Command | Nintendo Entertainment System | 1988 | Data East |
| Cobra Mission | Nintendo Entertainment System | 1994 | NTDEC |
| Cobra Triangle | Nintendo Entertainment System | 1989 | Rare Ltd. |
| Cocoron | Nintendo Entertainment System | 1991 | Takeru |
| Cocoto Festival | Wii | 2009 | Kylotonn |
| Cocoto Fishing Master | Wii | 2007 | Neko Entertainment |
| Cocoto Kart Racer | Nintendo GameCube, Wii | 2005 | Neko Entertainment |
| Cocoto Kart Racer 2 | Wii | 2011 | Neko Entertainment |
| Cocoto Magic Circus | Nintendo GameCube, Wii | 2006 | Neko Entertainment |
| Cocoto Platform Jumper | Nintendo GameCube, Wii | 2004 | Neko Entertainment |
| Cocoto Surprise | Wii | 2009 | Neko Entertainment |