| Who Framed Roger Rabbit | Nintendo Entertainment System | 1989 | Rare Ltd. |
| Who Wants to Be a Millionaire? | Wii | 2007 | Ludia |
| Whomp 'Em | Nintendo Entertainment System | 1990 | Jaleco |
| Wi-Fi Taiō: Gensen Table Games Wii | Wii | 2008 | Hudson Soft |
| Wicked Monsters Blast! | Wii | 2011 | Corecell Technology Co. Ltd. |
| Widget | Nintendo Entertainment System, Super Nintendo Entertainment System | 1992 | Atlus |
| Wii Chess | Wii | 2008 | Nintendo |
| Wii Fit | Wii | 2007 | Nintendo Entertainment Analysis & Development |
| Wii Fit Plus | Wii | 2009 | Nintendo Entertainment Analysis & Development |
| Wii Message Board | Wii | 2006 | Nintendo |
| Wii Music | Wii | 2008 | Nintendo Entertainment Analysis & Development |
| Wii Party | Wii | 2010 | Nintendo Cube |
| Wii Play | Wii | 2006 | Nintendo Entertainment Analysis & Development |
| Wii Play: Motion | Wii | 2011 | skip Ltd., Vanpool, Good-Feel, Nintendo Cube, Prope, Arzest, Chunsoft, Nintendo, Mitchell Corporation |
| Wii Sports | Wii | 2006 | Nintendo Entertainment Analysis & Development |
| Wii Sports Resort | Wii | 2009 | Nintendo Entertainment Analysis & Development |
| Wild Adventures:Ultimate Deer Hunt 3D | Nintendo 3DS | 2013 | EV Interactive |
| Wild Gunman | Nintendo Entertainment System | 1984 | Nintendo Research & Development 1 |
| Wild Guns | Super Nintendo Entertainment System | 1994 | Winning Entertainment Group |
| Wild West Guns | Wii | 2008 | Gameloft |
| WildSnake | Super Nintendo Entertainment System | 1994 | Bullet-Proof Software |
| Williams Arcade's Greatest Hits | Super Nintendo Entertainment System | 1996 | Backbone Entertainment |
| Willow | Nintendo Entertainment System | 1989 | Capcom |
| Wily & Right no RockBoard: That's Paradise | Nintendo Entertainment System | 1993 | Capcom |
| Win, Lose or Draw | Nintendo Entertainment System | 1988 | Running with Scissors |
| Wing Commander | Super Nintendo Entertainment System | 1990 | Origin Systems |
| Wing Island | Wii | 2006 | CAProduction |
| Winnie the Pooh's Rumbly Tumbly Adventure | Nintendo GameCube | 2005 | — |
| Winning Post | Super Nintendo Entertainment System | 1993 | Koei |
| Winning Post 7 Maximum 2008 | Wii | 2008 | Koei |
| Winter | Wii | — | n-Space |
| Winter Games | Nintendo Entertainment System | 1985 | Epyx |
| Winter Gold | Super Nintendo Entertainment System | 1996 | Funcom |
| Winter Olympics | Super Nintendo Entertainment System, Game Boy | 1993 | Tiertex Design Studios |
| Winter Sports 2011: Go for Gold | Wii | 2010 | 49Games |
| Winter Sports 2012: Feel the Spirit | Nintendo 3DS, Wii | 2011 | Independent Arts Software |
| Winter Sports 2: The Next Challenge | Wii | 2008 | 49Games |
| Winter Sports: The Ultimate Challenge | Wii | 2007 | 49Games |
| Winter Stars | Wii | 2011 | 49Games |
| Wipeout 2 | Nintendo 3DS, Wii | 2011 | Behaviour Interactive |
| Wipeout 3 | Wii | 2012 | Behaviour Interactive |
| Wipeout: Create & Crash | Wii | 2013 | Behaviour Interactive |
| Wipeout: The Game | Wii | 2010 | Acronym |
| Witch and Hero | Nintendo 3DS | 2012 | — |
| Witch and Hero II | Nintendo 3DS | 2012 | — |
| Witch n' Wiz (NES) | Nintendo Entertainment System | 2021 | — |
| Wizap!: King of Darkness | Super Nintendo Entertainment System | 1994 | — |
| Wizardry II: The Knight of Diamonds | Nintendo Entertainment System, Apple II series | 1982 | Sir-Tech |
| Wizardry III: Legacy of Llylgamyn | Nintendo Entertainment System | 1983 | Sir-Tech |
| Wizardry V: Heart of the Maelstrom | Super Nintendo Entertainment System | 1988 | Sir-Tech |
| Wizardry VI: Bane of the Cosmic Forge | Super Nintendo Entertainment System | 1990 | Sir-Tech |
| Wizards & Warriors | Nintendo Entertainment System | 1987 | Rare Ltd. |
| Wizards & Warriors III: Kuros: Visions of Power | Nintendo Entertainment System | 1992 | Zippo Games |
| Wizards & Warriors X: The Fortress of Fear | Game Boy | 1990 | Rare Ltd. |
| Wolfchild | Super Nintendo Entertainment System | 1992 | Core Design |
| Wolfenstein 3D | Super Nintendo Entertainment System, Apple II series | 1992 | Nerve Software, Raven Software, id Software, Interplay Entertainment |
| Wolverine | Nintendo Entertainment System | 1991 | Software Creations |
| Wolverine: Adamantium Rage | Super Nintendo Entertainment System | 1994 | Perfect Entertainment |
| Wonder Project J | Super Nintendo Entertainment System | 1994 | Givro |
| Wonder World Amusement Park | Wii | 2008 | Majesco Entertainment |