| OutRun 2006: Coast 2 Coast | Nintendo GameCube | 2006 | Sumo Digital |
| Over Horizon | Nintendo Entertainment System | 1991 | Hot B |
| Over the Hedge | Nintendo GameCube | 2006 | Blizzard Albany, Edge of Reality |
| Overlord: Dark Legend | Wii | 2009 | Climax Studios |
| Overturn | Wii | 2008 | Studio Zan |
| P.N.03 | Nintendo GameCube | 2003 | Capcom |
| P.O.W.: Prisoners of War | Nintendo Entertainment System | 1988 | SNK |
| P.T.O. | Super Nintendo Entertainment System | 1989 | Koei |
| P.T.O. II | Super Nintendo Entertainment System | 1994 | Koei |
| Pac 'n Roll | Wii | 2005 | Namco |
| Pac-Attack | Super Nintendo Entertainment System | 1993 | Namco |
| Pac-In-Time | Super Nintendo Entertainment System, Game Boy | 1994 | Kalisto Entertainment |
| Pac-Land | Nintendo Entertainment System | 1984 | Namco |
| Pac-Man | Nintendo Entertainment System, Super Nintendo Entertainment System, Apple II series | 1980 | Namco |
| Pac-Man & Galaga Dimensions | Nintendo 3DS | 2011 | Bandai Namco Entertainment |
| Pac-Man 2: The New Adventures | Super Nintendo Entertainment System | 1994 | Namco |
| Pac-Man and the Ghostly Adventures | Nintendo 3DS | 2013 | Monkey Bar Games |
| Pac-Man and the Ghostly Adventures 2 | Nintendo 3DS | 2014 | Monkey Bar Games |
| Pac-Man Fever | Nintendo GameCube | 2002 | Mass Media Inc. |
| Pac-Man Party | Nintendo 3DS, Wii | 2010 | Namco Networks |
| Pac-Man Vs. | Nintendo GameCube | 2003 | Nintendo Entertainment Analysis & Development |
| Pac-Man World 2 | Nintendo GameCube | 2002 | Namco Hometek Inc. |
| Pac-Man World 3 | Nintendo GameCube | 2005 | Namco |
| Pac-Man World Rally | Nintendo GameCube | 2006 | WildWorks |
| Pac-Mania | Nintendo Entertainment System | 1987 | Namco |
| Pachi-Slot Adventure | Nintendo Entertainment System | 1991 | C-Dream |
| Pachicom | Nintendo Entertainment System | 1985 | Bear's |
| Pacific Liberator | Wii | 2009 | Team6 Game Studios |
| Packy and Marlon | Super Nintendo Entertainment System | 1995 | — |
| Paddington: Adventures in London | Nintendo 3DS | 2015 | Neko Entertainment |
| Painter Momopii | Game Boy | 1990 | — |
| Pajama Sam: No Need to Hide When It's Dark Outside | Wii | 1996 | Humongous Entertainment |
| Paladin's Quest | Super Nintendo Entertainment System | 1992 | — |
| Palamedes | Nintendo Entertainment System, Game Boy | 1990 | Taito |
| Pallurikio | Wii | 2009 | Playstos Entertainment |
| Pandora's Tower | Wii | 2011 | Ganbarion |
| Panel Action Bingo | Game Boy | 1993 | — |
| Panel de Pon | Super Nintendo Entertainment System | 1995 | Intelligent Systems |
| Pang | Game Boy | 1989 | Capcom |
| Panic in Nakayoshi World | Super Nintendo Entertainment System | 1994 | — |
| Panic Restaurant | Nintendo Entertainment System | 1992 | EIM |
| Paper Mario | Wii | 2000 | Intelligent Systems |
| Paper Mario: Sticker Star | Nintendo 3DS | 2012 | Nintendo |
| Paper Mario: The Thousand-Year Door | Nintendo GameCube | 2004 | Intelligent Systems |
| Paper Plane | Nintendo GameCube, Nintendo 3DS | 2003 | Intelligent Systems, Nintendo Software Planning & Development, Nintendo Research & Development 1 |
| Paper Wars: Cannon Fodder | Wii | 2010 | Draw Distance |
| Paperboy | Nintendo Entertainment System, Game Boy | 1985 | Atari Games |
| Paperboy 2 | Nintendo Entertainment System, Super Nintendo Entertainment System, Game Boy | 1991 | Tengen |
| Papuwa | Super Nintendo Entertainment System | 1994 | — |
| Parallel World | Nintendo Entertainment System | 1990 | EIM |
| Parascientific Escape: Cruise in the Distant Seas | Nintendo 3DS | 2014 | Intense Limited |
| Parasol Henbē: Niji no Daibōken | Game Boy | 1990 | — |
| Parasol Henbē: Otogi no Kuni wa Ōsawagi! | Nintendo Entertainment System | 1991 | Sakata SAS Co., Ltd. |
| Parasol Stars: The Story Of Rainbow Islands 2 | Nintendo Entertainment System | 1991 | Taito |
| Parodius! From Myth to Laughter | Nintendo Entertainment System, Super Nintendo Entertainment System | 1990 | Konami |
| Party Pigs: FarmYard Games | Wii | 2009 | Neckar |
| Pathway | Nintendo 3DS | 2019 | Robotality |
| Pawapuro | Super Nintendo Entertainment System | 1995 | — |
| Paws & Claws Pet Resort | Wii | 2008 | THQ |
| Paws & Claws: Pet Vet | Wii | 2008 | Neopica |