| Final Fantasy Legend II | Game Boy | 1990 | Square |
| Final Fantasy Legend III | Game Boy | 1991 | Square |
| Final Fantasy Mystic Quest | Super Nintendo Entertainment System | 1992 | Square |
| Final Fantasy V | Super Nintendo Entertainment System | 1992 | Square |
| Final Fantasy VI | Super Nintendo Entertainment System | 1994 | Square |
| Final Fantasy VII | Nintendo Entertainment System | 2005 | Shenzhen Nanjing Technology Co., Ltd. |
| Final Fight | Super Nintendo Entertainment System | 1989 | Capcom |
| Final Fight 2 | Super Nintendo Entertainment System | 1993 | Capcom |
| Final Fight 3 | Super Nintendo Entertainment System | 1995 | Capcom |
| Final Lap | Nintendo Entertainment System | 1987 | Namco |
| Final Set | Super Nintendo Entertainment System | 1993 | — |
| Final Stretch | Super Nintendo Entertainment System | 1993 | Genki |
| Finding Nemo | Nintendo GameCube | 2003 | Traveller's Tales |
| Finding Nemo: Escape to the Big Blue | Nintendo GameCube, Nintendo 3DS | 2006 | — |
| Fire Blade | Nintendo GameCube | 2002 | Kuju Ltd. |
| Fire Emblem Awakening | Nintendo 3DS | 2012 | Intelligent Systems |
| Fire Emblem Echoes: Shadows of Valentia | Nintendo 3DS | 2017 | Intelligent Systems |
| Fire Emblem Fates: Birthright | Nintendo 3DS | 2015 | — |
| Fire Emblem Fates: Conquest | Nintendo 3DS | 2015 | — |
| Fire Emblem Fates: Revelation | Nintendo 3DS | 2015 | Intelligent Systems |
| Fire Emblem Fates: Special Edition | Nintendo 3DS | 2015 | Intelligent Systems |
| Fire Emblem Gaiden | Nintendo Entertainment System, Nintendo 3DS, Wii | 1992 | Intelligent Systems |
| Fire Emblem: Genealogy of the Holy War | Super Nintendo Entertainment System, Wii | 1996 | Intelligent Systems |
| Fire Emblem: Mystery of the Emblem | Super Nintendo Entertainment System, Wii | 1994 | Intelligent Systems |
| Fire Emblem: Path of Radiance | Nintendo GameCube | 2005 | Intelligent Systems |
| Fire Emblem: Radiant Dawn | Wii | 2007 | Nintendo Software Planning & Development |
| Fire Emblem: Shadow Dragon and the Blade of Light | Nintendo Entertainment System, Nintendo 3DS, Wii | 1990 | Intelligent Systems, Nintendo Research & Development 1 |
| Fire Emblem: The Sacred Stones | Nintendo 3DS | 2004 | Intelligent Systems |
| Fire Emblem: Thracia 776 | Super Nintendo Entertainment System, Wii | 1999 | Intelligent Systems |
| Fire ProWrestling 3: Legend Bout | Wii | 1992 | Human Entertainment |
| FireHawk | Nintendo Entertainment System | 1991 | Codemasters |
| Firestriker | Super Nintendo Entertainment System | 1993 | — |
| Fireteam Rogue | Super Nintendo Entertainment System | — | Accolade |
| Firework Thrower Kantaro's 53 Stations of the Tokaido | Nintendo Entertainment System | 1986 | Sunsoft |
| First Queen | Super Nintendo Entertainment System | 1988 | Kure Software Koubou |
| First Samurai | Super Nintendo Entertainment System | 1991 | Vivid Image |
| Fish Dude | Game Boy | 1990 | — |
| Fish Tank | Wii | 2011 | Draw Distance |
| Fish'em All | Wii | 2009 | Abylight |
| Fishdom H2O: Hidden Odyssey | Nintendo 3DS | 2009 | Playrix, Cypronia |
| Fisher-Price: Perfect Fit | Nintendo Entertainment System | 1990 | GameTek |
| Fishing Master | Wii | 2007 | Hudson Soft |
| Fishing Master World Tour | Wii | 2008 | Hudson Soft |
| Fishing Resort | Wii | 2011 | Prope |
| Fist of the North Star | Nintendo Entertainment System | 1987 | Shouei System |
| Fit & Fun | Wii | 2011 | Funbox Media |
| Fit in Six | Wii | 2011 | Ubisoft Blue Byte |
| Fizzball | Wii | 2009 | Replay Games, Grubby Games |
| Flappy | Nintendo Entertainment System | 1983 | dB-SOFT |
| Flash Hiders | Super Nintendo Entertainment System | 1993 | Right Stuff |
| Flashback | Super Nintendo Entertainment System | 1992 | Delphine Software International |
| FlatOut | Wii | 2010 | Team6 Game Studios |
| Flight of the Intruder | Nintendo Entertainment System | 1990 | Rowan Software |
| FlingSmash | Wii | 2010 | Artoon |
| Flip's Twisted World | Wii | 2010 | Frozen North Productions |
| Flipnote Studio 3D | Nintendo 3DS | 2013 | Nintendo Entertainment Analysis & Development |
| Fluidity | Wii | 2010 | Curve Games |
| Fluidity: Spin Cycle | Nintendo 3DS | 2012 | Curve Games |
| Flushed Away | Nintendo GameCube | 2006 | Monkey Bar Games, Altron, Art Co., Ltd |
| Flying Dragon: The Secret Scroll | Nintendo Entertainment System | 1989 | Culture Brain |