| The Adventures of Rad Gravity | Nintendo Entertainment System | 1990 | Interplay Entertainment |
| The Adventures of Rocky and Bullwinkle and Friends | Nintendo Entertainment System, Super Nintendo Entertainment System, Game Boy | 1992 | Imagineering |
| The Adventures of Star Saver | Game Boy | 1991 | — |
| The Adventures of Tintin: Prisoners of the Sun | Super Nintendo Entertainment System | — | Infogrames |
| The Adventures of Tintin: The Secret of the Unicorn | Nintendo 3DS, Wii | 2011 | Ubisoft |
| The Adventures of Tom Sawyer | Nintendo Entertainment System | 1989 | Winkysoft |
| The Alliance Alive | Nintendo 3DS | 2017 | Cattle Call |
| The Amazing Race | Wii | 2010 | Ludia |
| The Amazing Spider-Man | PlayStation Vita, Nintendo 3DS, Wii | 2012 | Gameloft, Beenox |
| The Amazing Spider-Man | Game Boy | 1990 | Rare Ltd. |
| The Amazing Spider-Man 2 | Game Boy | 1992 | Bits Studios |
| The Amazing Spider-Man: Lethal Foes | Super Nintendo Entertainment System | 1995 | — |
| The Ant Bully | Nintendo GameCube, Wii | 2006 | Behaviour Interactive |
| The Aquatic Games Starring James Pond and the Aquabats | Super Nintendo Entertainment System | 1992 | — |
| The Astyanax | Nintendo Entertainment System | 1989 | Aicom |
| The Atlas | Super Nintendo Entertainment System | 1991 | Artdink |
| The Bachelor: The Videogame | Wii | 2010 | Ludia |
| The Bard's Tale | Nintendo Entertainment System | 1985 | Interplay Entertainment |
| The Bard's Tale II: The Destiny Knight | Nintendo Entertainment System | 1986 | Interplay Entertainment |
| The Baseball 2003 | Nintendo GameCube | 2003 | Konami |
| The Battle of Olympus | Nintendo Entertainment System | 1988 | Radical Entertainment |
| The Beatles: Rock Band | Wii | 2009 | Harmonix Music Systems |
| The Biggest Loser | Wii | 2009 | Blitz Games Studios |
| The Biggest Loser Challenge | Wii | 2010 | Blitz Games Studios |
| The Bigs | Wii | 2007 | Capcom Vancouver |
| The Bigs 2 | Wii | 2009 | Capcom Vancouver |
| The Black Bass | Nintendo Entertainment System | 1987 | Hot B |
| The Black Bass | Nintendo Entertainment System | 1988 | Another |
| The Black Eyed Peas Experience | Wii | 2011 | Ubisoft Quebec |
| The Black Onyx | Nintendo Entertainment System | 1984 | Henk Rogers |
| The Blue Crystal Rod | Super Nintendo Entertainment System | 1994 | GAME STUDIO Inc. |
| The Blue Marlin | Nintendo Entertainment System | 1991 | Hot B |
| The Blues Brothers | Nintendo Entertainment System | 1991 | Titus Interactive |
| The Blues Brothers: Jukebox Adventure | Super Nintendo Entertainment System, Game Boy | 1993 | — |
| The Brainies | Super Nintendo Entertainment System | 1991 | — |
| The Bugs Bunny Birthday Blowout | Nintendo Entertainment System | 1990 | Kemco |
| The Bugs Bunny Crazy Castle 2 | Game Boy | 1991 | Kemco |
| The Cages: Pro Style Batting Practice | Wii | 2009 | Alpha Unit |
| The Chaos Engine | Super Nintendo Entertainment System | 1993 | The Bitmap Brothers |
| The Chessmaster | Nintendo Entertainment System, Game Boy | 1989 | The Software Toolworks |
| The Chronicles of Narnia: Prince Caspian | Wii | 2008 | Traveller's Tales |
| The Chronicles of Narnia: The Lion, the Witch and the Wardrobe | Nintendo GameCube | 2005 | Traveller's Tales |
| The Chronicles of Narnia: The Voyage of the Dawn Treader | Wii | 2010 | Fox Digital Entertainment |
| The Combatribes | Super Nintendo Entertainment System | 1990 | Technōs Japan |
| The Conduit | Wii | 2009 | High Voltage Software |
| The Croods: Prehistoric Party! | Nintendo 3DS, Wii | 2013 | Torus Games |
| The Cube | Nintendo 3DS, Wii | 2012 | Funbox Media |
| The Daring Game for Girls | Wii | 2009 | WXP |
| The Death and Return of Superman | Super Nintendo Entertainment System | 1994 | Blizzard Entertainment |
| The Denpa Men 2: Beyond the Waves | Nintendo 3DS | 2013 | Genius Sonority |
| The Denpa Men 3: The Rise of Digitoll | Nintendo 3DS | 2013 | Genius Sonority |
| The Denpa Men: They Came By Wave | Nintendo 3DS | 2012 | Genius Sonority |
| The Destiny of Zorro | Wii | 2008 | Pronto Games |
| The Dog Island | Wii | 2007 | Yuke's |
| The Duel: Test Drive II | Super Nintendo Entertainment System | 1989 | Distinctive Software |
| The Earth Fighter Rayieza | Nintendo Entertainment System | 1987 | Enix |
| The Fair | Game Boy | 2023 | — |
| The Fairly OddParents: Breakin' da Rules | Nintendo GameCube | 2003 | Blitz Games |
| The Fairly OddParents: Shadow Showdown | Nintendo GameCube | 2004 | ImaginEngine |
| The Final Fantasy Legend | Game Boy | 1989 | Square |