| Bonkers | Super Nintendo Entertainment System | 1994 | Capcom |
| Bonnie's Brunch | Nintendo 3DS | 2011 | — |
| Bonsai Barber | Wii | 2009 | Zoonami |
| Booby Kids | Nintendo Entertainment System | 1987 | Nichibutsu |
| Boogerman: A Pick and Flick Adventure | Super Nintendo Entertainment System | 1994 | Interplay Entertainment |
| Boogie | Wii | 2007 | EA Montreal |
| Boogie Superstar | Wii | 2008 | EA Montreal |
| Boom Blox | Wii | 2008 | Danger Close Games |
| Boom Blox Bash Party | Wii | 2009 | Amblin Entertainment |
| Boomer's Adventure in ASMIK World | Game Boy | 1989 | — |
| Boot Camp Academy | Wii | 2010 | Ubisoft |
| Boulder Dash | Nintendo Entertainment System, Game Boy, Apple II series | 1984 | Aackosoft, First Star Software |
| Boulder Dash-XL | Nintendo 3DS | 2011 | — |
| BoxBoxBoy! | Nintendo 3DS | 2016 | HAL Laboratory |
| BoxBoy! | Nintendo 3DS | 2015 | HAL Laboratory |
| Boxing | Game Boy | 1990 | Tose Co. |
| Boxing Legends of the Ring | Super Nintendo Entertainment System | 1993 | Sculptured Software |
| Boxxle | Game Boy | 1989 | Thinking Rabbit |
| Brain Age: Concentration Training | Nintendo 3DS | 2013 | Nintendo Software Planning & Development |
| Brain Challenge | Wii | 2007 | Gameloft Software Beijing, Gameloft |
| Brain Drain | Game Boy | 1998 | Visual Impact |
| Brain Lord | Super Nintendo Entertainment System | 1994 | Produce! |
| Bram Stoker's Dracula | Nintendo Entertainment System, Super Nintendo Entertainment System | 1993 | Traveller's Tales |
| Bram Stoker's Dracula | Game Boy | 1993 | Acclaim Studios London |
| Brandish | Super Nintendo Entertainment System | 1991 | Nihon Falcom |
| Bratz Girlz Really Rock | Wii | 2008 | Blitz Games |
| Bratz Kidz | Wii | 2008 | Neko Entertainment |
| Bratz: Forever Diamondz | Nintendo GameCube | 2006 | Blitz Games |
| Bratz: Rock Angelz | Nintendo GameCube | 2005 | Blitz Games |
| Bratz: The Movie | Wii | 2007 | Blitz Games |
| Brave | Wii | 2012 | Behaviour Interactive |
| Brave Dungeon | Nintendo 3DS | 2016 | — |
| Brave: A Warrior's Tale | Wii | 2009 | VIS Entertainment, Collision Studios |
| Bravely Default | Nintendo 3DS | 2012 | Square Enix, Silicon Studio |
| Bravely Second: End Layer | Nintendo 3DS | 2015 | Square Enix, Silicon Studio |
| Brawl Brothers | Super Nintendo Entertainment System | 1992 | Jaleco |
| Break Time: The National Pool Tour | Nintendo Entertainment System | 1993 | Pony Canyon |
| BreakThru | Nintendo Entertainment System | 1986 | Data East |
| BreakThru! | Super Nintendo Entertainment System | 1994 | Zoo Corporation |
| Breath of Fire | Super Nintendo Entertainment System | 1993 | Capcom |
| Breath of Fire II | Super Nintendo Entertainment System | 1994 | Capcom |
| Brett Hull Hockey | Super Nintendo Entertainment System | 1994 | Radical Entertainment |
| Brett Hull Hockey '95 | Super Nintendo Entertainment System | 1995 | Radical Entertainment |
| Broken Saints | Wii | — | Gnosis Games |
| Broken Sword: Shadow of the Templars – The Director's Cut | Wii | 2009 | Revolution Software |
| Bronkie the Bronchiasaurus | Super Nintendo Entertainment System | 1995 | — |
| Brothers in Arms: Double Time | Wii | 2008 | Gearbox Software |
| Brothers in Arms: Earned in Blood | Wii | 2005 | Gearbox Software |
| Brothers in Arms: Road to Hill 30 | Wii | 2005 | Gearbox Software |
| Bruiser and Scratch | Wii | 2008 | Steel Penny Games |
| Brunswick Pro Bowling | Nintendo 3DS, Wii | 2007 | Point of View, Inc. |
| Brunswick World: Tournament of Champions | Super Nintendo Entertainment System | 1997 | Tiertex Design Studios |
| Brunswick Zone Cosmic Bowling | Wii | 2010 | CokeM Interactive |
| Brutal: Paws of Fury | Super Nintendo Entertainment System | 1994 | GameTek |
| BS F-Zero 2 Grand Prix | Super Nintendo Entertainment System | 1996 | Nintendo |
| BS F-Zero Grand Prix | Super Nintendo Entertainment System | 1996 | — |
| BS Fire Emblem: Archanea Senki-hen | Super Nintendo Entertainment System | 1997 | Intelligent Systems |
| BS Tantei Club: Yuki ni Kieta Kako | Super Nintendo Entertainment System | 1997 | Nintendo Research & Development 1 |
| BS The Legend of Zelda | Super Nintendo Entertainment System | 1995 | Nintendo Research & Development 2 |
| BS The Legend of Zelda: Ancient Stone Tablets | Super Nintendo Entertainment System | 1997 | Nintendo Research & Development 2 |