| Street Racer | 1994 | — |
| Strike Gunner S.T.G | 1992 | Athena |
| Striker | 1992 | Rage Games |
| Stunt Race FX | 1994 | Nintendo Entertainment Analysis & Development |
| Sugoi Hebereke | 1994 | Sunsoft, OLM, Inc. |
| Sugoro Quest++: Dicenics | 1994 | — |
| Sugoroku Ginga Senki | 1996 | Bottom Up |
| Sunset Riders | 1991 | Konami |
| Super 3D Noah's Ark | 1994 | Wisdom Tree |
| Super Adventure Island | 1992 | Produce! |
| Super Adventure Island II | 1994 | Hudson Soft |
| Super Air Diver | 1993 | — |
| Super Back to the Future Part II | 1993 | GameFAQs |
| Super Baseball Simulator 1.000 | 1991 | Culture Brain |
| Super Bases Loaded | 1991 | Tose Co. |
| Super Bases Loaded 2 | 1993 | Tose Co. |
| Super Bases Loaded 3 | 1994 | Tose Co. |
| Super Batter Up | 1992 | — |
| Super Battleship | 1993 | — |
| Super Battletank | 1992 | Imagineering |
| Super Battletank 2 | 1994 | Imagineering |
| Super Bikkuriman | 1993 | Bandai |
| Super Birdie Rush | 1992 | — |
| Super Bomberman | 1993 | Hudson Soft |
| Super Bomberman 2 | 1994 | Hudson Soft |
| Super Bomberman 3 | 1995 | Hudson Soft |
| Super Bomberman 4 | 1996 | Produce! |
| Super Bomberman 5 | 1997 | Hudson Soft |
| Super Bomberman: Panic Bomber W | 1995 | — |
| Super Bombliss | 1995 | — |
| Super Bonk | 1994 | Red Entertainment |
| Super Bowling | 1992 | KID |
| Super Buster Bros. | 1990 | Capcom |
| Super Caesars Palace | 1993 | Majesco Entertainment |
| Super Casino 2 | 1994 | — |
| Super Castlevania IV | 1991 | Konami |
| Super Chase H.Q. | 1992 | Taito |
| Super Chinese Fighter | 1995 | Culture Brain |
| Super Chinese World 2 | 1993 | Culture Brain |
| Super Chinese World 3 | 1995 | Culture Brain |
| Super Conflict | 1993 | EA Seattle |
| Super Dany | 1995 | Cryo Interactive |
| Super Dimension Fortress Macross: Scrambled Valkyrie | 1993 | Winkysoft |
| Super Double Dragon | 1992 | Technōs Japan |
| Super Drift Out: World Rally Championships | 1995 | — |
| Super Dropzone | 1994 | — |
| Super F-1 Hero | 1992 | Varie |
| Super F1 Circus | 1992 | — |
| Super Famicom Wars | 1998 | Intelligent Systems |
| Super Family Gerende | 1998 | — |
| Super Famista 2 | 1993 | — |
| Super Famista 3 | 1994 | — |
| Super Famista 4 | 1995 | — |
| Super Famista 5 | 1996 | — |
| Super Fire Pro Wrestling | 1991 | Human Entertainment |
| Super Fire Pro Wrestling 2 | 1992 | Human Entertainment |
| Super Fire Pro Wrestling 3 Final Bout | 1993 | Human Entertainment |
| Super Fire Pro Wrestling Special | 1994 | Human Entertainment |
| Super Fire Pro Wrestling X Premium | 1996 | Human Entertainment |
| Super Fire Pro Wrestling: Queen's Special | 1995 | — |