| SD Gundam Generation: Colony Kaku Senki | 1996 | Bandai |
| SD Gundam Generation: Gryps Senki | 1996 | Bandai |
| SD Gundam Generation: Ichinen Sensouki | 1996 | Bandai |
| SD Gundam Generation: Zanscare Senki | 1996 | Bandai |
| SD Gundam: G Next | 1995 | Bandai |
| SD Gundam: G Next - Unit & map collection | 1996 | Bandai |
| SD Gundam: GX | 1994 | Bandai |
| SD Gundam: Power Formation Puzzle | 1996 | Bandai |
| SD Kidō Senshi Gundam 2 | 1993 | Bandai |
| SD Kidō Senshi Gundam: V Sakusen Shidō | 1992 | Bandai |
| SD Mobile Suit Gundam | 1992 | — |
| SeaQuest DSV | 1994 | Sculptured Software |
| Secret of Evermore | 1995 | Square |
| Secret of Mana | 1993 | Square |
| Secret of the Stars | 1993 | Tecmo |
| Seifuku Densetsu Pretty Fighter | 1994 | Genki |
| Seijuu Maden: Beasts & Blades | 1996 | — |
| Sengoku | 1991 | SNK |
| Sensible Soccer | 1992 | Sensible Software |
| Sgt. Saunders' Combat! | 1995 | — |
| Shadow of the Beast | 1989 | Ubisoft Reflections |
| Shadowrun | 1993 | Krome Studios Melbourne |
| Shanghai III | 1993 | Success, Kuusoukagaku, Sunsoft |
| Shaq Fu | 1994 | Delphine Software International |
| Shien's Revenge | 1994 | Givro |
| Shigetaka Kashiwagi's Top Water Bassing | 1995 | — |
| Shijō Saikyō League Serie A: Ace Striker | 1995 | — |
| Shin Kidō Senki Gundam Wing: Endless Duel | 1996 | Winning Entertainment Group |
| Shin Megami Tensei | 1992 | Atlus |
| Shin Megami Tensei If… | 1994 | Atlus |
| Shin Megami Tensei II | 1994 | Atlus |
| Shin Momotaro Densetsu | 1993 | — |
| Shin Nekketsu Kōha: Kunio-tachi no Banka | 1994 | Givro |
| Shin Onigashima | 1987 | Nintendo Entertainment Analysis & Development, Pax Softnica |
| Shin SD Sengokuden: Daishōgun Retsuden | — | Bandai |
| Shin Seikoku: La Wares | 1995 | — |
| Shinseiki Odysselya | 1993 | — |
| Shinseiki Odysselya II | 1995 | — |
| Shiroi Ringu he | 1995 | — |
| Shodai Nekketsu Kouha Kunio-Kun | 1992 | — |
| Shutokō Battle '94: Drift King Tsuchiya Keiichi & Bandō Masaaki | 1994 | Genki |
| Shōgi Saikyō | 1994 | — |
| Shōnin yo Taishi wo Idake!! | 1995 | Fortyfive |
| Side Pocket | 1986 | Data East |
| Silva Saga II: The Legend of Light and Darkness | 1993 | SETA Corporation |
| Sim City | 1991 | Electronic Arts |
| SimAnt | 1991 | Maxis |
| SimCity | 1989 | Nintendo Entertainment Analysis & Development, Maxis |
| SimCity 2000 | 1993 | Maxis, Full Fat |
| SimEarth | 1990 | Maxis |
| SimTown | 1995 | Maxis |
| Simulation Pro Yakyū | 1995 | Hect |
| Sink or Swim | 1993 | Eutechnyx |
| Sky Mission | 1992 | — |
| Skyblazer | 1994 | Ukiyotei |
| Sküljagger: Revolt of the Westicans | 1992 | ASC Games |
| Slam Dunk | 1994 | Tose Co. |
| Slam Dunk 2: IH Yosen Kanzenban!! | 1995 | — |
| Slayers | 1994 | — |
| Smart Ball | 1991 | Game Freak |