| Dick Tracy | 1990 | Realtime Associates |
| Dig Dug | 1982 | Namco |
| Dino Breeder | 1997 | — |
| Dino Breeder 2 | 1998 | — |
| Dirty Racing | 1993 | Gremlin Interactive |
| Disney's Aladdin | 1993 | Virgin Interactive |
| Disney's Mulan | — | Tiertex Design Studios |
| Disney's Pocahontas | 1996 | Tiertex Design Studios, Funcom |
| Do I Pass | 2019 | Taylor McCue |
| Donkey Kong | 1994 | Nintendo Entertainment Analysis & Development |
| Donkey Kong Land | 1995 | Rare Ltd. |
| Donkey Kong Land 2 | 1996 | Rare Ltd. |
| Donkey Kong Land III | 1997 | Rare Ltd. |
| Double Dragon 3: The Rosetta Stone | 1990 | East Technology Corp. |
| Double Dragon II | 1990 | Technōs Japan |
| Downtown Special: Kunio-kun's Historical Period Drama! | 1991 | Technōs Japan |
| Dr. Franken | 1992 | Motivetime Ltd. |
| Dr. Mario | 1990 | Nintendo Research & Development 1 |
| Dragon Slayer | 1984 | Nihon Falcom |
| DragonHeart: Fire & Steel | 1996 | Funcom |
| DT: Lords of Genomes | 2001 | — |
| DuckTales | 1989 | Capcom |
| DuckTales 2 | 1993 | Capcom |
| Dungeon Land | 1992 | — |
| Dungeon Savior | 2000 | — |
| E-Motion | 1990 | The Assembly Line |
| Earthworm Jim | 1994 | Shiny Entertainment |
| Earthworm Jim: Menace 2 the Galaxy | 1999 | — |
| Elevator Action | 1983 | Taito |
| Elite Soccer | 1994 | — |
| Elite Soccer | 1994 | — |
| F-1 Hero MD | 1992 | Aisystem Tokyo |
| F-1 Race | 1984 | HAL Laboratory |
| F-1 Race | 1990 | — |
| Family Jockey | 1987 | Namco |
| Felix the Cat | 1992 | Sunsoft |
| FIFA 97 | 1996 | EA Vancouver |
| FIFA International Soccer | 1993 | EA Vancouver |
| FIFA: Road to World Cup 98 | 1997 | EA Vancouver |
| Final Fantasy Adventure | 1991 | Square |
| Final Fantasy Legend II | 1990 | Square |
| Final Fantasy Legend III | 1991 | Square |
| Fish Dude | 1990 | — |
| Foreman For Real | 1995 | Software Creations |
| Fortified Zone | 1991 | Jaleco |
| Frogger | 1981 | Konami |
| Future GPX Cyber Formula | 1992 | — |
| G Arms: Operation Gundam | 1991 | Bandai |
| Game & Watch Gallery | 1997 | — |
| Game Boy Gallery | 1995 | — |
| Game Boy Wars | 1991 | Hudson Soft, Intelligent Systems |
| Game Boy Wars Turbo | 1997 | — |
| Ganbare Goemon: Sarawareta Ebisumaru! | 1991 | Konami |
| Gargoyle's Quest | 1990 | Capcom |
| Gauntlet II | 1986 | Atari Games |
| GB Genjin Land: Viva! Chikkun Ōkoku | 1994 | Red Entertainment |
| Ghostbusters II | 1990 | HAL Laboratory |
| Go! Go! Tank | 1990 | — |
| God Medicine | 1993 | Konami |
| Godzilla | 1990 | Compile |