| Trax | 1991 | HAL Laboratory |
| Trip World | 1992 | Sunsoft |
| Trump Boy | — | Pack-In-Video |
| Trump Boy II | 1990 | Pack-In-Video |
| Turn and Burn: The F-14 Dogfight Simulator | 1992 | Imagineering |
| Turok: Battle of the Bionosaurs | 1997 | Bit Managers |
| Turrican | 1990 | Rainbow Arts, Factor 5 |
| TV Champion | 1994 | — |
| Uchū no Kishi: Tekkaman Blade | 1993 | — |
| Ultima: Runes of Virtue | 1991 | Origin Systems |
| Ultima: Runes of Virtue II | 1994 | Origin Systems |
| Ultimate Mortal Kombat 3 | 1996 | Midway Games |
| Ultra Golf | 1991 | Ultra Games |
| Undercover Cops: Hakaishin Garumaa | 1993 | Irem |
| Universal Soldier | 1992 | The Code Monkeys |
| Urban Strike | 1994 | — |
| Vexed | 2023 | — |
| Wario Blast | 1994 | Hudson Soft |
| Wario Land II | 1998 | Nintendo Research & Development 1 |
| Wario Land: Super Mario Land 3 | 1994 | Nintendo Research & Development 1 |
| Wave Race | 1992 | Nintendo Entertainment Analysis & Development |
| Wayne's World | 1993 | Radical Entertainment |
| WCW: The Main Event | 1994 | Krome Studios Melbourne |
| Who Framed Roger Rabbit | 1991 | Capcom |
| Winter Olympics | 1993 | Tiertex Design Studios |
| Wizards & Warriors X: The Fortress of Fear | 1990 | Rare Ltd. |
| World Bowling | 1990 | Athena |
| Worms | 1995 | Team17 |
| WWF Raw | 1994 | Sculptured Software |
| WWF Road to WrestleMania | 2001 | Winning Entertainment Group |
| WWF Superstars | 1992 | Rare Ltd. |
| WWF Superstars 2 | 1993 | Sculptured Software |
| WWF War Zone | 2013 | Sculptured Software |
| X | 1992 | Nintendo Entertainment Analysis & Development, Argonaut Games |
| Yakuman | 1989 | Intelligent Systems |
| Yogi Bear's Gold Rush | 1994 | — |
| Yoshi | 1991 | Game Freak |
| Yoshi's Cookie | 1992 | Bullet-Proof Software, Tose Co. |
| Yu Yu Hakusho | 1993 | — |
| Zen the Intergalactic Ninja | 1992 | — |
| Zen: Intergalactic Ninja | 1993 | Konami |
| Zoids Densetsu | 1990 | — |