| Best of Microsoft Entertainment Pack | 1995 | Microsoft |
| Beyond the Nexus | 1994 | Absolute Entertainment |
| Bill & Ted's Excellent Game Boy Adventure: A Bogus Journey! | 1991 | Krome Studios Melbourne |
| Bill Elliott's NASCAR Fast Tracks | 1991 | — |
| Bionic Commando | 1992 | Minakuchi Engineering Co., Ltd. |
| Black Bass: Lure Fishing | 1992 | Hot B |
| Blaster Master Jr. | 1991 | Aicom |
| Block Hole | 1990 | Konami |
| Bomb Jack | 1984 | Tecmo, Koei Tecmo Games |
| Bomberman GB | 1994 | Hudson Soft |
| Bomberman GB 2 | 1995 | Hudson Soft |
| Bomberman GB 3 | 1996 | — |
| Boomer's Adventure in ASMIK World | 1989 | — |
| Boulder Dash | 1984 | Aackosoft, First Star Software |
| Boxing | 1990 | Tose Co. |
| Boxxle | 1989 | Thinking Rabbit |
| Brain Drain | 1998 | Visual Impact |
| Bram Stoker's Dracula | 1993 | Acclaim Studios London |
| Bubble Bobble | 1986 | Taito |
| Bubble Bobble Part 2 | 1993 | Taito, OLM, Inc. |
| Bubsy 2 | 1994 | Accolade |
| Burai Fighter Deluxe | 1991 | — |
| Burgertime Deluxe | 1991 | — |
| Captain America and The Avengers | 1991 | Data East, Realtime Associates |
| Captain Tsubasa J: Zenkoku Seiha e no Chousen | 1995 | — |
| Captain Tsubasa VS | 1992 | — |
| Castlevania II: Belmont's Revenge | 1991 | Konami |
| Castlevania Legends | 1997 | Konami |
| Castlevania: The Adventure | 1989 | Konami |
| Catrap | 1990 | Asmik Ace Entertainment |
| Cave Noire | 1991 | Konami |
| Centipede | 1981 | Atari, Inc. |
| Chalvo 55 | 1997 | — |
| Championship Pool | 1993 | Bitmasters |
| Chase H.Q. | 1988 | Taito |
| Chikyū Kaihō Gun ZAS | 1992 | D Wonderland Inc. |
| Choplifter II | 1991 | Krome Studios Melbourne |
| Cliffhanger | 1993 | Rockstar Lincoln |
| Contra III: The Alien Wars | 1992 | Konami |
| Cool Spot | 1993 | Virgin Interactive |
| Cool World | 1992 | Twilight |
| Cosmo Tank | 1990 | — |
| Crash 'n' the Boys: Street Challenge | 1992 | Technōs Japan |
| Cult Jump | 1993 | — |
| Cutthroat Island | 1995 | Software Creations |
| Cyraid | 1990 | — |
| Daedalian Opus | 1990 | Tokai Communications |
| Daffy Duck | 1994 | Sunsoft |
| Dangan GB2 | 2023 | — |
| Darius | 1987 | Taito |
| Darkman | 1991 | Ocean Software, Twilight |
| Darkwing Duck | 1992 | Capcom |
| Dastardly and Muttley | 1992 | — |
| Days of Thunder | 1990 | Krome Studios Melbourne, Argonaut Games, Creative Materials, Tiertex Design Studios |
| Dead Heat Scramble | 1990 | — |
| Dead Names | 2024 | — |
| Deadeus | 2019 | — |
| Desert Strike | 1992 | Electronic Arts |
| Detective Conan: The Suspicious Gorgeous Train | 1998 | Tom Create |
| Dexterity | 1990 | SNK |