| Fantasy Zone II: The Tears of Opa-Opa | 1987 | Sega, Sunsoft |
| Faria: A World of Mystery and Danger | 1989 | Game Arts |
| Faxanadu | 1987 | Hudson Soft |
| Felix the Cat | 1992 | Sunsoft |
| Fester's Quest | 1989 | Sunsoft |
| Field Combat | 1985 | Tose Co. |
| Fighting Golf | 1988 | SNK, SNK |
| Fighting Road | 1988 | Toei Animation |
| Final Fantasy | 1987 | Square |
| Final Fantasy II | 1988 | Square |
| Final Fantasy III | 1990 | Square |
| Final Fantasy VII | 2005 | Shenzhen Nanjing Technology Co., Ltd. |
| Final Lap | 1987 | Namco |
| Fire Emblem Gaiden | 1992 | Intelligent Systems |
| Fire Emblem: Shadow Dragon and the Blade of Light | 1990 | Intelligent Systems, Nintendo Research & Development 1 |
| FireHawk | 1991 | Codemasters |
| Firework Thrower Kantaro's 53 Stations of the Tokaido | 1986 | Sunsoft |
| Fisher-Price: Perfect Fit | 1990 | GameTek |
| Fist of the North Star | 1987 | Shouei System |
| Flappy | 1983 | dB-SOFT |
| Flight of the Intruder | 1990 | Rowan Software |
| Flying Dragon: The Secret Scroll | 1989 | Culture Brain |
| Flying Hero | 1989 | Aicom |
| Flying Shark | 1987 | Bitwave Games, Toaplan, Software Creations |
| Flying Warriors | 1991 | Culture Brain |
| Formation Z | 1984 | Jaleco |
| Formula One: Built to Win | 1990 | Winkysoft |
| Frankenstein: The Monster Returns | 1991 | Tose Co. |
| Freedom Force | 1988 | Sunsoft |
| Friday the 13th | 1989 | Pack-In-Video |
| FROM BELOW - A Real NES Game! | 2020 | — |
| Front Line | 1982 | Taito |
| Fun House | 1991 | Realtime Associates |
| Fuzzical Fighter | 1991 | Make Software |
| G.I. Joe | 1991 | KID |
| G.I. Joe: The Atlantis Factor | 1992 | KID |
| Galactic Crusader | 1990 | Color Dreams |
| Galaga | 1981 | Namco |
| Galaga: Demons of Death | 1987 | Namco |
| Galaxian | 1979 | Namco |
| Galaxy 5000 | 1991 | Activision |
| Gambler Jiko Chūshinha 2 | 1990 | Asmik Ace Entertainment |
| Ganbare Goemon 2 | 1989 | Konami |
| Ganbare Goemon Gaiden 2: Tenka no Zaihō | 1992 | Konami |
| Ganbare Goemon Gaiden: Kieta Ōgon Kiseru | 1990 | Konami |
| Ganbare Goemon! Karakuri Dōchū | 1986 | Konami |
| Ganso Saiyūki: Super Monkey Daibōken | 1986 | Techno Quest |
| Gargoyle's Quest II | 1992 | Capcom |
| Gauntlet | 1987 | Tengen |
| Gauntlet II | 1986 | Atari Games |
| Geimos | 1985 | Micronics |
| Gekitotsu Yonku Battle | 1989 | VIS Entertainment |
| Gemfire | 1991 | Koei |
| Genghis Khan | 1987 | Koei |
| Genghis Khan II: Clan of the Gray Wolf | 1992 | Koei |
| Genpei Tōma Den | 1986 | Namco |
| Getsu Fūma Den | 1987 | Konami |
| Ghost Lion | 1989 | Kemco |
| Ghostbusters | 1984 | Activision |
| Ghostbusters II | 1990 | Dynamix |