| Datach | 1992 | Bandai |
| Day Dreamin' Davey | 1992 | Sculptured Software |
| Days of Thunder | 1990 | Krome Studios Melbourne, Argonaut Games, Creative Materials, Tiertex Design Studios |
| Deadly Towers | 1986 | Lenar |
| Death Race | 1990 | — |
| Deathbots | 1990 | Odyssey Software |
| Decathlon | 1992 | C&E |
| Deep Dungeon III: Yūshi e no Tabi | 1988 | Hummingbird Soft |
| Deep Dungeon IV: Kuro no Yōjutsushi | 1990 | Hummingbird Soft |
| Defender of the Crown | 1986 | Cinemaware |
| Defenders of Dynatron City | 1992 | Lucasfilm Games |
| Demon Sword | 1988 | Tose Co. |
| Desert Commander | 1988 | Kemco |
| Destination Earthstar | 1990 | Imagineering |
| Destiny of an Emperor | 1989 | Capcom |
| Devil World | 1984 | Nintendo |
| Dezaemon | 1991 | Athena |
| Dian Shi Mali | 1989 | — |
| Dick Tracy | 1990 | Realtime Associates |
| Die Hard | 1991 | Pack-In-Video |
| Dig Dug | 1982 | Namco |
| Dig Dug II | 1985 | Namco |
| Digger T. Rock | 1990 | Rare Ltd. |
| Digital Devil Story: Megami Tensei | 1987 | Atlus |
| Digital Devil Story: Megami Tensei II | 1990 | Atlus |
| Dirty Harry | 1990 | Mindscape |
| Disney's Aladdin | 1993 | Virgin Interactive |
| Dizzy: Prince of the Yolkfolk | 1991 | Big Red Software |
| Doki! Doki! Yūenchi: Crazy Land Daisakusen | 1991 | KID |
| Don Doko Don | 1989 | Taito |
| Don Doko Don 2 | 1992 | Taito |
| Donald Land | 1988 | Data East |
| Donkey Kong | 1981 | Nintendo Research & Development 1, Ikegami Tsushinki, Nintendo |
| Donkey Kong 3 | 1984 | Nintendo |
| Donkey Kong Classics | 1988 | Nintendo Entertainment Analysis & Development, Nintendo |
| Donkey Kong Jr. | 1982 | Nintendo |
| Donkey Kong Jr. Math | 1983 | Nintendo Research & Development 2 |
| Dooly Bravo Land | 1992 | Daou Infosys |
| Door Door | 1983 | Koichi Nakamura |
| Doraemon | 1986 | Hudson Soft |
| Doraemon: Giga Zombie no Gyakushū | 1990 | Epoch Co. |
| Double Dare | 1988 | Rare Ltd. |
| Double Dragon | 1987 | Technōs Japan |
| Double Dragon II: The Revenge | 1989 | Technōs Japan |
| Double Dragon III: The Sacred Stones | 1991 | Technōs Japan |
| Double Dribble | 1987 | Konami |
| Double Moon Densetsu | 1992 | Nippon Computer Systems |
| Double Strike | 1990 | — |
| Dough Boy | 1985 | Synapse Software |
| Downtown Nekketsu March: Super-Awesome Field Day! | 1990 | Technōs Japan |
| Downtown Special: Kunio-kun's Historical Period Drama! | 1991 | Technōs Japan |
| Dr. Chaos | 1987 | Pony Canyon |
| Dr. Jekyll and Mr. Hyde | 1988 | Advance Communication |
| Dr. Mario | 1990 | Nintendo Research & Development 1 |
| Drac's Night Out | 1991 | — |
| Dragon Ball 3: Gokūden | 1989 | Tose Co. |
| Dragon Ball Z III: Ressen Jinzou Ningen | 1992 | Tose Co. |
| Dragon Ball Z Side Story: Plan to Eradicate the Saiyans | 1993 | Tose Co. |
| Dragon Ball: Daimaō fukkatsu | 1988 | Bandai |
| Dragon Buster | 1985 | Namco |