| Epic Mickey 2: The Power of Two | 2012 | Junction Point Studios, Blitz Games Studios, Heavy Iron Studios |
| Equilibrio | 2009 | DK-Games, Fishing Cactus |
| Escape from Bug Island | 2006 | Spike |
| EscapeVektor | 2011 | Nnooo |
| Esper Dream | 1987 | Konami |
| ESWAT: City Under Siege | 1990 | Sega |
| Eternity's Child | 2008 | SilverSphereStudios, Luc Bernard |
| Evasive Space | 2009 | High Voltage Software |
| Everybody Votes Channel | 2007 | Nintendo |
| Everyone Sing | 2012 | Gusto Games |
| Excite Truck | 2006 | Monster Games |
| Excitebike | 1984 | Nintendo Research & Development 1 |
| Excitebike: World Rally | 2009 | Monster Games |
| ExciteBots: Trick Racing | 2009 | Monster Games |
| ExerBeat | 2011 | Bandai Namco Entertainment |
| ExZeus | 2007 | HyperDevbox Japan |
| Eyeshield 21: Field Saikyō no Senshi Tachi | 2007 | Hiroki Tsurumoto |
| F1 2009 | 2009 | Sumo Digital |
| FaceBreaker | 2008 | EA Vancouver |
| Famicom Tantei Club Part II: Ushiro ni Tatsu Shōjo | 1989 | Tose Co. |
| Famicom Wars | 1988 | Intelligent Systems |
| Family & Friends Party | 2009 | Gammick Entertainment |
| Family Card Games | 2009 | Arc System Works |
| Family Fest Presents Movie Games | 2008 | Kuju Ltd. |
| Family Feud: 2010 Edition | 2009 | Ludia |
| Family Feud: 2012 Edition | 2011 | Ludia |
| Family Feud: Decades | 2010 | Ludia |
| Family Fun Football | 2009 | Seamless Entertainment, Inc. |
| Family Gameshow | 2009 | Zushi Games Ltd |
| Family Glide Hockey | 2008 | Arc System Works |
| Family Jockey | 2008 | Bandai Namco Entertainment |
| Family Mini Golf | 2009 | Arc System Works |
| Family Party: 30 Great Games | 2008 | Tamsoft |
| Family Party: 30 Great Games Outdoor Fun | 2009 | Tamsoft |
| Family Party: 30 Great Games Winter Fun | 2010 | Tamsoft |
| Family Party: Fitness Fun | 2010 | Tamsoft |
| Family Pirate Party | 2009 | Arc System Works |
| Family Slot Car Racing | 2009 | Arc System Works |
| Family Table Tennis | 2008 | Arc System Works |
| Fantastic Four: Rise of the Silver Surfer | 2007 | Visual Concepts |
| Fantasy Aquarium World | 2009 | Coresoft |
| Far Cry Vengeance | 2006 | Ubisoft Montreal |
| Fast Draw Showdown | 1994 | American Laser Games |
| Fast Food Panic | 2009 | Dorasu |
| Fast Racing League | 2011 | Shin'en Multimedia |
| Fatal Frame: Mask of the Lunar Eclipse | 2008 | Grasshopper Manufacture |
| Ferrari Challenge: Trofeo Pirelli | 2008 | Eutechnyx |
| Ferrari: The Race Experience | 2010 | Eutechnyx |
| FIFA 08 | 2007 | EA Vancouver |
| FIFA 09 | 2008 | EA Vancouver |
| FIFA 10 | 2009 | EA Vancouver |
| FIFA 11 | 2010 | EA Vancouver |
| FIFA 12 | 2011 | EA Vancouver |
| FIFA 13 | 2012 | EA Vancouver |
| FIFA 14 | 2013 | EA Vancouver |
| FIFA 15 | 2014 | EA Vancouver |
| Final Fantasy | 1987 | Square |
| Final Fantasy Crystal Chronicles: Echoes of Time | 2009 | Square Enix |
| Final Fantasy Crystal Chronicles: My Life as a Darklord | 2009 | Square Enix |
| Final Fantasy Crystal Chronicles: My Life as a King | 2008 | Square Enix |