| Disney's Chicken Little: Ace in Action | 2006 | Avalanche Software |
| Diva Girls: Divas on Ice | 2009 | Arc System Works |
| Dive: The Medes Islands Secret | 2010 | Over the Top Games |
| DJ Hero | 2009 | Ubisoft Leamington |
| DJ Hero 2 | 2010 | Ubisoft Leamington |
| Doc Louis's Punch-Out!! | 2009 | Next Level Games |
| Doctor Who: Return to Earth | 2010 | Asylum Entertainment |
| Dodge Racing: Charger vs. Challenger | 2009 | Extra Mile Studios |
| Dokapon Kingdom | 2007 | Sting |
| Don King Boxing | 2009 | 2K China |
| Donkey Kong Barrel Blast | 2007 | Paon DP |
| Donkey Kong Country | 1994 | Rare Ltd. |
| Donkey Kong Country Returns | 2010 | Retro Studios |
| Donkey Kong Jungle Beat | 2004 | Nintendo Entertainment Analysis & Development |
| Dood's Big Adventure | 2010 | Rainbow Studios |
| Dora the Explorer: Dora Saves the Crystal Kingdom | 2009 | High Voltage Software |
| Dora the Explorer: Dora Saves the Snow Princess | 2008 | High Voltage Software |
| Dora the Explorer: Dora's Big Birthday Adventure | 2010 | High Voltage Software |
| Doraemon Wii | 2007 | Eighting |
| Double Dragon II: The Revenge | 1989 | Technōs Japan |
| Doubutsu Kisoutengai | 2008 | Success |
| Dr. Mario Online Rx | 2008 | Arika |
| Dr. Robotnik's Mean Bean Machine | 1993 | Sonic Team |
| Dracula: Undead Awakening | 2009 | Moregames Entertainment |
| Dragon Ball Z: Budokai Tenkaichi 3 | 2007 | Spike |
| Dragon Ball: Revenge of King Piccolo | 2009 | Media.Vision |
| Dragon Blade: Wrath of Fire | 2007 | D3 Publisher |
| Dragon Quest | 1986 | Chunsoft |
| Dragon Quest 25 Shuunen Kinen: Famicom & Super Famicom Dragon Quest I-II-III | 2011 | Square Enix |
| Dragon Quest 25 Shūnen Kinen Famicom & Super Famicom Dragon Quest I・II・III | 2011 | Square Enix |
| Dragon Quest Swords | 2007 | Genius Sonority |
| Dragon Quest X | 2012 | Square Enix, Yuji Horii |
| Dragon Quest: Monster Battle Road | 2008 | Eighting |
| Dragon Saber | 1990 | Namco |
| Dragon's Lair Trilogy | 2010 | Digital Leisure, Dimitrij |
| Drawn to Life: The Next Chapter | 2009 | Planet Moon Studios |
| Dream Dance & Cheer | 2009 | indiePub |
| Dream Pinball 3D | 2008 | TopWare Interactive |
| Dream Salon | 2009 | CyberPlanet Interactive |
| Driift Mania | 2009 | Konami |
| Drill Sergeant Mindstrong | 2009 | Xseed Games |
| Driver: Parallel Lines | 2006 | Ubisoft Reflections |
| Driver: San Francisco | 2011 | Ubisoft Reflections |
| EA Playground | 2007 | EA Vancouver |
| EA Sports Active | 2009 | EA Vancouver |
| EA Sports Active 2 | 2010 | EA Vancouver |
| EA Sports Active NFL Training Camp | 2010 | EA Vancouver |
| EA Sports Active: More Workouts | 2009 | Jędrzej Kitowicz |
| Earth Seeker | 2011 | Crafts & Meister |
| Eco Shooter: Plant 530 | 2009 | Intelligent Systems |
| Eduardo the Samurai Toaster | 2009 | Semnat Studios |
| El Chavo | 2012 | Kaxan Games |
| Elebits | 2006 | Konami |
| Emeraldia | 1993 | Namco |
| Emergency Heroes | 2008 | Ubisoft Reflections |
| Emergency Mayhem | 2008 | Supersonic Software |
| Endless Ocean | 2007 | Arika |
| Endless Ocean 2: Adventures of the Deep | 2009 | Arika |
| Ennichi no Tatsujin | 2006 | Bandai Namco Holdings |
| Epic Mickey | 2010 | Junction Point Studios |