| Lunar Pool | 1985 | Compile |
| Lupin III: Pandora no Isan | 1987 | Tose Co. |
| M.C. Kids | 1992 | Visual Concepts, Virgin Interactive, Arc Developments |
| M.U.L.E. | 1983 | Ozark Softscape |
| Mach Rider | 1985 | Nintendo Research & Development 2 |
| Mad Max | 1990 | Mindscape |
| Magic Darts | 1991 | Romstar |
| Magic Jewelry | 1990 | Hwang Shinwei |
| Magic Johnson's Fast Break | 1988 | Arcadia Systems |
| Magician | 1991 | Eurocom |
| MagMax | 1986 | Nichibutsu |
| Major League Baseball | 1988 | Atlus |
| Majō Densetsu II: Daimashikyō Galious | 1987 | Konami |
| Maniac Mansion | 1987 | Lucasfilm Games |
| Mappy | 1984 | Namco |
| Mappy Kids | 1989 | Namco |
| Mappy-Land | 1986 | Tose Co. |
| Marble Madness | 1984 | Atari Games |
| Mario Bros. | 1984 | Nintendo |
| Mario Is Missing! | 1993 | The Software Toolworks |
| Mario's Time Machine | 1993 | Mindscape |
| Master Chu and the Drunkard Hu | 1989 | Thin Chen Enterprise |
| Master Takahashi's Adventure Island IV | 1994 | Hudson Soft |
| Masuzoe Youichi: Asa Made Famicom | 1992 | Coconuts Japan |
| Mechanized Attack | 1989 | SNK |
| Mega Man | 1987 | Capcom |
| Mega Man 2 | 1988 | Capcom |
| Mega Man 3 | 1990 | Capcom |
| Mega Man 4 | 1991 | Capcom |
| Mega Man 5 | 1992 | Capcom |
| Mega Man 6 | 1993 | Capcom |
| Meitantei Holmes: M-Kara no Chousenjou | 1989 | Another |
| Menace Beach | 1990 | Color Dreams |
| Mendel Palace | 1989 | Game Freak |
| Metal Fighter | 1989 | Thin Chen Enterprise |
| Metal Gear | 1987 | Konami |
| Metal Max | 1991 | Crea-Tech |
| Metal Mech | 1990 | Sculptured Software |
| Metal Slader Glory | 1991 | HAL Laboratory |
| Metal Storm | 1991 | GameFAQs |
| Metro-Cross | 1985 | Namco |
| Metroid | 1986 | Nintendo Research & Development 1 |
| Mezase! Top Pro: Green ni Kakeru Yume | 1993 | Tose Co. |
| Michael Andretti's World GP | 1988 | Human Entertainment |
| Mickey Mousecapade | 1987 | Hudson Soft |
| Mickey's Adventures in Numberland | 1994 | Krome Studios Melbourne |
| Mickey's Safari in Letterland | 1993 | Krome Studios Melbourne |
| Micro Machines | 1991 | Codemasters |
| Micro Mages | 2019 | Morphcat Games |
| MiG-29: Soviet Fighter | 1989 | Codemasters |
| Might and Magic Book One: The Secret of the Inner Sanctum | 1990 | New World Computing |
| Mighty Bomb Jack | 1986 | Tecmo |
| Mighty Final Fight | 1993 | Capcom |
| Millipede | 1982 | Atari, Inc. |
| Milon's Secret Castle | 1986 | Hudson Soft |
| Minelvaton Saga: Ragon no Fukkatsu | 1987 | Random House |
| Mini-Putt | 1987 | Artech Digital Entertainment |
| Miracle Piano Teaching System | 1990 | Mindscape |
| Miracle Ropitt: 2100-Nen no Daibōken | 1987 | Micronics |
| Miracle Warriors: Seal of the Dark Lord | 1986 | Kogado Studio |