| 2006 FIFA World Cup | Nintendo GameCube | EA Vancouver |
| Actionloop | Wii | Mitchell Corporation |
| Adventure Bar Story | Nintendo 3DS | — |
| Avatar: The Last Airbender | Nintendo GameCube, Wii | Tose Co., Halfbrick Studios, THQ Studio Australia |
| Barnyard | Nintendo GameCube, Wii | Blue Tongue Entertainment |
| Baten Kaitos Origins | Nintendo GameCube | tri-Crescendo |
| Battle Stadium D.O.N | Nintendo GameCube | Eighting |
| Billy the Wizard: Rocket Broomstick Racing | Wii | Data Design Interactive |
| Bionicle Heroes | Nintendo GameCube, Wii | TT Games |
| Blazing Angels: Squadrons of WWII | Wii | Ubisoft Romania |
| Bleach: Shattered Blade | Wii | Polygon Magic |
| Bratz: Forever Diamondz | Nintendo GameCube | Blitz Games |
| Bully | Wii | Rockstar New England, Rockstar Toronto, Rockstar Vancouver |
| Cake Mania | Wii | Sandlot Games |
| Call of Duty 3 | Wii | Treyarch, Exakt Entertainment |
| Cars | Nintendo GameCube, Wii | Rainbow Studios, Helixe, Locomotive Games, Beenox |
| Castle of Shikigami III | Wii | Alfa System |
| Chibi-Robo! | Nintendo GameCube, Wii | skip Ltd. |
| Cocoto Magic Circus | Nintendo GameCube, Wii | Neko Entertainment |
| Crayon Shin-chan: Saikyō Kazoku Kasukabe King Wii | Wii | Banpresto |
| Curious George | Nintendo GameCube | Monkey Bar Games |
| Dave Mirra BMX Challenge | Wii | Left Field Productions |
| De Blob | Wii | THQ Nordic, Universomo, Ronimo Games, Blue Tongue Entertainment |
| Dead Rising | Wii | Capcom |
| Deal or No Deal | Wii | Cat Daddy Games, Imagination Games, Black Lantern Studios, Inc., Vimukti Technologies |
| Death Jr. II: Root of Evil | Wii | Backbone Entertainment |
| Disney's Chicken Little: Ace in Action | Wii | Avalanche Software |
| Driver: Parallel Lines | Wii | Ubisoft Reflections |
| Elebits | Wii | Konami |
| Ennichi no Tatsujin | Wii | Bandai Namco Holdings |
| Escape from Bug Island | Wii | Spike |
| Excite Truck | Wii | Monster Games |
| Far Cry Vengeance | Wii | Ubisoft Montreal |
| FIFA 07 | Nintendo GameCube | EA Vancouver |
| FIFA Street 2 | Nintendo GameCube | EA Vancouver |
| Finding Nemo: Escape to the Big Blue | Nintendo GameCube, Nintendo 3DS | — |
| Flushed Away | Nintendo GameCube | Monkey Bar Games, Altron, Art Co., Ltd |
| Fort Boyard: The Game | Wii | Dream On Studio, Mindscape, Mad Monkey Studio |
| Franklin: A Birthday Surprise | Nintendo GameCube | — |
| GT Pro Series | Wii | MTO |
| Guilty Gear XX Accent Core | Wii | Arc System Works |
| Happy Feet | Nintendo GameCube, Wii | Behaviour Interactive |
| Ice Age 2: The Meltdown | Nintendo GameCube, Wii | Eurocom |
| Jacked | Nintendo GameCube | Sproing Interactive Media |
| Jikkyō Powerful Major League | Nintendo GameCube | — |
| Kororinpa | Wii | Hudson Soft |
| Lego Star Wars II: The Original Trilogy | Nintendo GameCube | Traveller's Tales |
| Luxor 2 | Wii | MumboJumbo |
| Madden NFL 07 | Nintendo GameCube, Wii | EA Orlando |
| Major League Baseball 2K6 | Nintendo GameCube | Visual Concepts |
| Marvel: Ultimate Alliance | Wii | Raven Software |
| Mega Man X Collection | Nintendo GameCube | Capcom |
| Metal Slug Anthology | Wii | Terminal Reality |
| Monster 4x4: World Circuit | Wii | Ubisoft Barcelona |
| Monster House | Nintendo GameCube | Behaviour Interactive |
| Mortal Kombat: Armageddon | Wii | Midway Games |
| Myth Makers: Super Kart GP | Wii | Data Design Interactive |
| Need for Speed: Carbon | Nintendo GameCube, Wii | EA Vancouver |
| Nicktoons: Battle for Volcano Island | Nintendo GameCube | Blue Tongue Entertainment |
| Odama | Nintendo GameCube | Vivarium Inc. |
| One Piece: Grand Adventure | Nintendo GameCube | Ganbarion |
| Open Season | Nintendo GameCube, Wii | Ubisoft Montreal |
| Orbient | Wii | skip Ltd. |
| OutRun 2006: Coast 2 Coast | Nintendo GameCube | Sumo Digital |
| Over the Hedge | Nintendo GameCube | Blizzard Albany, Edge of Reality |
| Pac-Man World Rally | Nintendo GameCube | WildWorks |
| Pimp My Ride | Wii | Eutechnyx |
| Pokémon Battle Revolution | Wii | Genius Sonority |
| Puyo Puyo! 15th Anniversary | Wii | Sonic Team |
| Puzzle Challenge: Crosswords and More | Wii | Supersonic Software |
| Rampage: Total Destruction | Nintendo GameCube, Wii | Pipeworks Software |
| Rapala Tournament Fishing | Wii | Modus Studios Bucharest |
| Rayman Raving Rabbids | Wii | Ubisoft Montpellier |
| Rebel Raiders: Operation Nighthawk | Wii | Kando Games |
| Red Steel | Wii | Ubisoft Paris |
| Rockstar Games presents Table Tennis | Wii | Rockstar San Diego |
| Rogue Trooper | Wii | Rebellion Developments |
| Romance of the Three Kingdoms XI | Wii | Koei |
| Runaway 2: The Dream of the Turtle | Wii | Pendulo Studios, S.L. |
| Safecracker: The Ultimate Puzzle Adventure | Wii | Kheops Studio |
| Sam & Max Save the World | Wii | Telltale Games |
| Scarface: The World Is Yours | Wii | Radical Entertainment |
| SD Gundam: Scad Hammers | Wii | Bandai |
| Secret Files: Tunguska | Wii | Animation Arts |
| Sengoku Basara 2 | Wii | Capcom |
| Shrek Smash n' Crash Racing | Nintendo GameCube | Torus Games |
| Sonic Riders | Nintendo GameCube | Sonic Team |
| SpongeBob SquarePants: Creature from the Krusty Krab | Nintendo GameCube, Wii | Blitz Games |
| Star Trek: Tactical Assault | Game Boy | Quicksilver Software |
| Super Fruit Fall | Wii | Aqua Pacific |
| Super Monkey Ball Adventure | Nintendo GameCube | Traveller's Tales |
| Super Monkey Ball: Banana Blitz | Wii | Sega |
| Super Swing Golf | Wii | Ntreev Soft |
| Tamagotchi: Party On! | Wii | h.a.n.d. |
| Teen Titans | Nintendo GameCube | Behaviour Interactive |
| The Ant Bully | Nintendo GameCube, Wii | Behaviour Interactive |
| The Godfather | Wii | Visceral Games |
| The Grim Adventures of Billy & Mandy | Nintendo GameCube, Wii | High Voltage Software |
| The Legend of Spyro: A New Beginning | Nintendo GameCube | The Mighty Troglodytes, Krome Studios, Amaze Entertainment |
| The Sims 2: Pets | Nintendo GameCube, Wii | Maxis |
| The Sims 2: Pets | Nintendo GameCube, Wii | Visceral Games, Maxis |
| Tiger Woods PGA Tour 07 | Wii | EA Sports |
| Tom Clancy's Splinter Cell: Double Agent | Nintendo GameCube, Wii | Ubisoft Shanghai |
| Tomb Raider: Legend | Nintendo GameCube | Crystal Dynamics |
| Tony Hawk's Downhill Jam | Wii | Blizzard Albany |
| Toribash | Wii | Nabi Studios |
| Trauma Center: Second Opinion | Wii | Atlus |
| Ultimate Duck Hunting | Wii | Mid Carolina Media |
| WarioWare: Smooth Moves | Wii | Intelligent Systems, Nintendo Software Planning & Development |
| Wii Message Board | Wii | Nintendo |
| Wii Play | Wii | Nintendo Entertainment Analysis & Development |
| Wii Sports | Wii | Nintendo Entertainment Analysis & Development |
| Wing Island | Wii | CAProduction |
| World Series of Poker: Tournament of Champions | Wii | Left Field Productions |
| X-Men: The Official Game | Nintendo GameCube | Underground Development |
| Ōkami | Wii | Clover Studio |