| Mario & Sonic at the Olympic Winter Games | 2009 | Sonic Team, Racjin |
| Mario Kart Wii | 2008 | Nintendo Entertainment Analysis & Development |
| Mario Party 8 | 2007 | Hudson Soft |
| Mario Party 9 | 2012 | Nintendo Cube |
| Mario Power Tennis | 2004 | Camelot Software Planning |
| Mario Sports Mix | 2010 | Square Enix |
| Mario Strikers Charged | 2007 | Next Level Games |
| Mario Super Sluggers | 2008 | Bandai Namco Entertainment |
| Mart Racer | 2009 | Joju Games |
| Martian Panic | 2010 | N-Fusion Interactive |
| Marvel Land | 1990 | Namco |
| Marvel Super Hero Squad | 2009 | Blue Tongue Entertainment |
| Marvel Super Hero Squad: Comic Combat | 2011 | Griptonite Games |
| Marvel Super Hero Squad: The Infinity Gauntlet | 2010 | Griptonite Games |
| Marvel Super Heroes 3D: Grandmaster's Challenge | 2010 | Neko Entertainment |
| Marvel: Ultimate Alliance | 2006 | Raven Software |
| Marvel: Ultimate Alliance 2 | 2009 | Blizzard Albany |
| Matchman | 2008 | — |
| Mathews Bowhunting | 2010 | Zoo Corporation |
| Max & the Magic Marker | 2010 | Press Play |
| Maximum Racing: Drag & Stock Racer | 2010 | Brain in a Jar |
| Maximum Racing: GP Classic Racing | 2010 | Brain in a Jar |
| Medal of Honor: Heroes 2 | 2007 | Danger Close Games |
| Medal of Honor: Vanguard | 2007 | Budcat Creations |
| Medieval games | 2009 | N-Fusion Interactive |
| Meet the Robinsons | 2007 | Climax Studios |
| Mega Man | 1987 | Capcom |
| Mega Man 10 | 2010 | Inti Creates |
| Mega Man 9 | 2008 | Inti Creates |
| Mega Man X | 1993 | Capcom |
| Megamind: Mega Team Unite | 2010 | THQ Studio Australia |
| Megamind: Ultimate Showdown | 2010 | THQ |
| Mercury Meltdown Revolution | 2007 | UTV Ignition Games |
| Merv Griffin's Crosswords | 2008 | Pipeworks Software |
| Metal Slug Anthology | 2006 | Terminal Reality |
| Metroid Prime | 2002 | Retro Studios |
| Metroid Prime 2: Echoes | 2004 | Retro Studios |
| Metroid Prime 3: Corruption | 2007 | Retro Studios |
| Metroid Prime: Trilogy | 2009 | Retro Studios |
| Metroid: Other M | 2010 | D-Rockets, Nintendo Software Planning & Development, Team Ninja |
| MIB: Alien Crisis | 2012 | Modus Studios Bucharest |
| Miburi & Teburi | 2008 | Climax Entertainment |
| Michael Jackson: The Experience | 2010 | Ubisoft Montpellier |
| Midnight Bowling | 2008 | Gameloft |
| Milestone Shooting Collection 2 | 2010 | Milestone |
| Military Madness: Nectaris | 2009 | Backbone Entertainment |
| Mini Desktop Racing | 2005 | Data Design Interactive |
| Mini Golf Resort | 2010 | Rambo: The Video Game |
| Mini Ninjas | 2008 | IO Interactive |
| MiniCopter: Adventure Flight | 2007 | Sonic Powered |
| Minna no Jōshikiryoku Terebi | 2008 | HAL Laboratory |
| Minon: Everyday Hero | 2007 | Red Entertainment |
| Minute to Win It | 2010 | Smack Down Productions |
| MLB Power Pros | 2007 | Konami |
| MLB Power Pros 2008 | 2008 | Konami |
| MLB Superstars | 2008 | Deep Fried Entertainment |
| Mobile Suit Gundam: MS Sensen 0079 | 2007 | Bandai |
| Mom-chan Diet Wii Figureobics by Jung Da-Yeon | 2010 | Mechanic Arms |
| Momotaro Dentetsu 16: Moving in Hokkaido! | 2007 | Hudson Soft |
| Monkey Mischief: Party Time | 2008 | Nordcurrent |