| Skies of Arcadia | 2000 | Sega Wow |
| Smashing Drive | 2002 | Gaelco |
| Smuggler's Run | 2000 | Rebellion Developments, Rockstar San Diego |
| Smuggler's Run: Warzones | 2002 | Rockstar San Diego |
| Sonic & Knuckles | 1994 | Sonic Team |
| Sonic 3 & Knuckles | 1994 | Sonic Team |
| Sonic Adventure | 1998 | Sonic Team, Now Production |
| Sonic Adventure 2 | 2001 | Sonic Team |
| Sonic Adventure 2: Battle | 2002 | Sonic Team |
| Sonic Adventure DX: Director's Cut | 2003 | Sonic Team |
| Sonic Gems Collection | 2005 | Sonic Team |
| Sonic Heroes | 2003 | Sonic Team |
| Sonic Mega Collection | 2002 | Sonic Team |
| Sonic Riders | 2006 | Sonic Team |
| Sonic the Fighters | 1996 | Sega AM2 |
| Sonic the Hedgehog | 1991 | Sonic Team, Konami |
| Sonic the Hedgehog 2 | 1992 | Sonic Team |
| Sonic the Hedgehog CD | 1993 | Sonic Team |
| Soulcalibur II | 2002 | Project Soul |
| Space Raiders | 2002 | Taito |
| Spartan: Total Warrior | 2005 | Creative Assembly |
| Spawn: Armageddon | 2003 | Point of View, Inc. |
| Special Jinsei Game | 2003 | Takara |
| Speed Challenge: Jacques Villeneuve's Racing Vision | 2002 | Ubisoft |
| Speed Kings | 2003 | Climax Studios |
| Sphinx and the Cursed Mummy | 2003 | THQ Nordic, Eurocom |
| Spider-Man | 2002 | Treyarch, Gray Matter Interactive |
| Spider-Man 2 | 2004 | Treyarch |
| SpongeBob SquarePants: Battle for Bikini Bottom | 2003 | Heavy Iron Studios |
| SpongeBob SquarePants: Creature from the Krusty Krab | 2006 | Blitz Games |
| SpongeBob SquarePants: Lights, Camera, Pants! | 2005 | THQ |
| SpongeBob SquarePants: Revenge of the Flying Dutchman | 2002 | Blizzard Albany |
| Spy Hunter | 1983 | Midway Games |
| Spy Hunter | 2001 | Paradigm Entertainment |
| Spyro: A Hero's Tail | 2004 | Eurocom |
| Spyro: Enter the Dragonfly | 2002 | — |
| SSX 3 | 2003 | EA Vancouver |
| SSX On Tour | 2005 | EA Vancouver |
| SSX Tricky | 2001 | EA Vancouver |
| Star Fox Adventures | 2002 | Rare Ltd. |
| Star Fox: Assault | 2005 | Bandai Namco Entertainment |
| Star Wars Jedi Knight II: Jedi Outcast | 2002 | Raven Software |
| Star Wars Rogue Squadron II: Rogue Leader | 2001 | Factor 5 |
| Star Wars Rogue Squadron III: Rebel Strike | 2003 | Factor 5 |
| Star Wars: Bounty Hunter | 2002 | Lucasfilm Games |
| Star Wars: The Clone Wars | 2002 | Pandemic Studios |
| Starsky & Hutch | 2003 | Mind's Eye Productions |
| Street Hoops | 2002 | Black Ops Entertainment |
| Street Racing Syndicate | 2004 | Eutechnyx |
| Strike Force Bowling | 2004 | — |
| Summoner 2 | 2002 | Volition |
| Sunny Garcia Surfing | 2001 | Krome Studios |
| Super Bubble Pop | 2002 | Zombie Studios |
| Super Mario 128 | — | Nintendo Entertainment Analysis & Development |
| Super Mario Strikers | 2005 | Next Level Games |
| Super Mario Sunshine | 2002 | Nintendo Entertainment Analysis & Development |
| Super Monkey Ball | 2001 | Amusement Vision |
| Super Monkey Ball 2 | 2002 | Amusement Vision |
| Super Monkey Ball Adventure | 2006 | Traveller's Tales |
| Super Puzzle Bobble | 2000 | Taito |